LEADER 04474nam 22007335 450 001 9910409699203321 005 20220316150055.0 010 $a3-030-42282-8 024 7 $a10.1007/978-3-030-42282-0 035 $a(CKB)4100000011040046 035 $a(DE-He213)978-3-030-42282-0 035 $a(MiAaPQ)EBC6176541 035 $a(PPN)243761481 035 $a(EXLCZ)994100000011040046 100 $a20200415d2020 u| 0 101 0 $aeng 135 $aurnn#008mamaa 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 14$aThe Biochemistry of Retinoid Signaling III$b[electronic resource] $eVitamin A and Retinoic Acid in Embryonic Development /$fedited by Mary Ann Asson-Batres, Cecile Rochette-Egly 205 $a1st ed. 2020. 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2020. 215 $a1 online resource (VII, 229 p. 42 illus., 38 illus. in color.) 225 1 $aSubcellular Biochemistry,$x0306-0225 ;$v95 311 $a3-030-42280-1 327 $aChapter 1. How Dietary Deficiency Studies have Illuminated the Many Roles of Vitamin A during Development and Postnatal Life -- Chapter 2. Maternal-fetal Transfer of Vitamin A and its Impact on Mammalian Embryonic Development -- Chapter 3. Retinoic Acid-Regulated Target Genes during Development: Integrative Genomics Analysis -- Chapter 4. RA Signaling in Limb Development and Regeneration in Different Species -- Chapter 5. Retinoic Acid Signaling and Heart Development -- Chapter 6. Retinoic Acid Signaling and Development of the Respiratory System -- Chapter 7. Retinoic Acid Signaling and Zebrafish Dentition during Development and Evolution -- Chapter 8. Fetal Alcohol Spectrum Disorder: Embryogenesis under Reduced Retinoic Acid Signaling Conditions. 330 $aThis book covers subjects that have major impacts on society, such as the mechanism of maternal-fetal transfer of vitamin A, and the effects of alcohol on retinoic acid signaling and mammalian embryonic development. There has been an awareness of the importance of consuming vitamins throughout human history, but empirical studies of their physiological role and mode of action only began about 150 years ago. Since then, the biochemical nature of vitamin A and its active derivative, retinoic acid, have been identified and researchers around the globe have investigated retinoic acid?s physiological function in growth processes and in maintaining life Written by leading experts, this book discusses the latest findings and advances in retinoic acid research. It addresses topics such as the role of retinoic acid signaling in a multitude of processes, including limb, heart and respiratory system development, as well as its role in maintaining postnatal organ systems. This book is a valuable resource for scientists involved in vitamin A/retinoic acid research and readers interested in developmental biology. 410 0$aSubcellular Biochemistry,$x0306-0225 ;$v95 606 $aHuman physiology 606 $aNutrition    606 $aEmbryology 606 $aPhysiology 606 $aHuman Physiology$3https://scigraph.springernature.com/ontologies/product-market-codes/B13004 606 $aNutrition$3https://scigraph.springernature.com/ontologies/product-market-codes/C18000 606 $aEmbryology$3https://scigraph.springernature.com/ontologies/product-market-codes/L18010 606 $aPhysiology$3https://scigraph.springernature.com/ontologies/product-market-codes/L33000 606 $aRetinoides$2thub 606 $aVitamina A$2thub 606 $aEmbriologia$2thub 606 $aFisiologia humana$2thub 608 $aLlibres electrònics$2thub 615 0$aHuman physiology. 615 0$aNutrition   . 615 0$aEmbryology. 615 0$aPhysiology. 615 14$aHuman Physiology. 615 24$aNutrition. 615 24$aEmbryology. 615 24$aPhysiology. 615 7$aRetinoides 615 7$aVitamina A 615 7$aEmbriologia 615 7$aFisiologia humana 676 $a612.399 702 $aAsson-Batres$b Mary Ann$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aRochette-Egly$b Cecile$4edt$4http://id.loc.gov/vocabulary/relators/edt 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910409699203321 996 $aThe Biochemistry of Retinoid Signaling III$92507522 997 $aUNINA