LEADER 04520nam 22007215 450 001 9910409692603321 005 20220427113633.0 010 $a981-15-3449-7 024 7 $a10.1007/978-981-15-3449-2 035 $a(CKB)4100000011264516 035 $a(MiAaPQ)EBC6207838 035 $a(DE-He213)978-981-15-3449-2 035 $a(PPN)248394975 035 $a(EXLCZ)994100000011264516 100 $a20200522d2020 u| 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aEpigenetics in Allergy and Autoimmunity /$fedited by Christopher Chang, Qianjin Lu 205 $a1st ed. 2020. 210 1$aSingapore :$cSpringer Singapore :$cImprint: Springer,$d2020. 215 $a1 online resource (408 pages) 225 1 $aAdvances in Experimental Medicine and Biology,$x0065-2598 ;$v1253 311 $a981-15-3448-9 320 $aIncludes bibliographical references. 327 $aEpigenetics in health and disease -- The development of epigenetics in the study of disease pathogenesis -- Epigenetic methods and twin studies -- The role of genetics, the environment and epigenetics in atopic dermatitis -- The epigenetics of food allergy -- Epigenetics and the Environment in allergy and asthma: asthma and allergic rhinitis -- Epigenetics of lupus erythematosus -- Epigenetics of psoriasis -- The role of epigenetics in type 1 diabetes -- Epigenetics of Primary Biliary Cholangitis -- Epigenetics in primary Sjogren?s syndrome -- Epigenetics in Multiple Sclerosis -- The epigenetic regulation of Scleroderma and its clinical application. 330 $aThis book will address the growing roles of epigenetics in disease pathogenesis, and review the contribution of epigenetic modifications to disease onset and progression. The roles that epigenetics plays in facilitating effects of the environment on allergy and immunologic diseases will be reviewed. The book is divided into three parts ? the first is an introduction to epigenetics and the methods that have been developed to study epigenetics, the second addresses epigenetics in allergic diseases and the third part will cover epigenetics in autoimmune diseases. With the rapid expansion of knowledge of how genes are regulated and how this regulation affects disease phenotypes, this book will be attractive to experienced researchers as well as those just launching an epigenetics research program. It will also be of interest to allergist, immunologists, rheumatologists and dermatologist who are engaged in clinical practice as a resource for understanding the basis for personalized and precision medicine. For example, the role that epigenetics plays in the pathogenesis in various allergic and autoimmune disorders and how this determines disease phenotypes will be covered extensively in this book. This book will thus help fill the gap in available resources on epigenetics in allergy and autoimmune diseases. 410 0$aAdvances in Experimental Medicine and Biology,$x0065-2598 ;$v1253 606 $aImmunology 606 $aPosttranslational modification 606 $aRheumatology 606 $aAllergy 606 $aImmunology$3https://scigraph.springernature.com/ontologies/product-market-codes/B14000 606 $aPosttranslational Modification$3https://scigraph.springernature.com/ontologies/product-market-codes/L14090 606 $aRheumatology$3https://scigraph.springernature.com/ontologies/product-market-codes/H33170 606 $aAllergology$3https://scigraph.springernature.com/ontologies/product-market-codes/H11009 606 $aEpigenètica$2thub 606 $aAl·lèrgia$2thub 606 $aSistema immunitari$2thub 608 $aLlibres electrònics$2thub 615 0$aImmunology. 615 0$aPosttranslational modification. 615 0$aRheumatology. 615 0$aAllergy. 615 14$aImmunology. 615 24$aPosttranslational Modification. 615 24$aRheumatology. 615 24$aAllergology. 615 7$aEpigenètica 615 7$aAl·lèrgia 615 7$aSistema immunitari 676 $a572.865 702 $aChang$b Christopher$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aLu$b Qianjin$4edt$4http://id.loc.gov/vocabulary/relators/edt 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910409692603321 996 $aEpigenetics in Allergy and Autoimmunity$92517108 997 $aUNINA