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010   $a981-15-1580-8
024 7 $a10.1007/978-981-15-1580-4
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035   $a(DE-He213)978-981-15-1580-4
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035   $a(PPN)243229488
035   $a(EXLCZ)995300000000003643
100   $a20200309d2020      u|         0
101 0 $aeng
135   $aurnn|008mamaa
181   $ctxt$2rdacontent
182   $cc$2rdamedia
183   $acr$2rdacarrier
200 10$aLectin in Host Defense Against Microbial Infections /$fedited by Shie-Liang Hsieh
205   $a1st ed. 2020.
210  1$aSingapore :$cSpringer Singapore :$cImprint: Springer,$d2020.
215   $a1 online resource (XIV, 230 p. 25 illus., 21 illus. in color.) 
225 1 $aAdvances in Experimental Medicine and Biology,$x0065-2598 ;$v1204
311   $a981-15-1579-4 
320   $aIncludes bibliographical references.
327   $aC-type Lectin Receptors in Antifungal Immunity -- Immune recognition of pathogen-derived glycolipids through Mincle -- CLEC5A: A promiscuous pattern recognition receptor to microbes and beyond -- Collectins: Innate immune pattern recognition molecules -- Insect C-type lectins in microbial infections -- Galectins in Host Defense against Microbial Infections -- Galectins in Host-Pathogen Interactions: Structural, Functional and Evolutionary Aspects -- Siglecs at the Host-Pathogen Interface -- Siglecs that associate with DAP12.
330   $aThis book systemically presents the latest research on lectins, covering all the major topics in the field, including the heterocomplex of lectins and Toll-like receptors, protective versus pathogenic functions in connection with microbial infections, and novel strategies for enhancing host immunity against infectious diseases caused by viruses, bacteria, and fungi. Lectins are a large group of glycan-binding proteins that recognize diverse glycan and non-glycan structures expressed on prokaryotic and eukaryotic cells, and are vital to cell-cell interactions, the attachment of microbes to host cells, and the recognition and activation of immune responses to exogenous and endogenous danger signals. The composition and structure of microbes are complex and include numerous ?pathogen-associated molecular patterns? or ?damage-associated molecular patterns?. As such, microbes? interactions with immune cells activate multiple innate immunity receptors and produce distinct inflammatory reactions, which can be protective to contain microbial invasion, or pathogenic to cause tissue damage and shock syndrome in the host. The book shares lessons learned from state-of-the art research in this field, highlights the latest discoveries, and provides insightful discussions on lectin-mediated inflammatory reactions, while also outlining future research directions. .
410  0$aAdvances in Experimental Medicine and Biology,$x0065-2598 ;$v1204
606   $aImmunology
606   $aMedical microbiology
606   $aBiochemistry
606   $aImmunology$3https://scigraph.springernature.com/ontologies/product-market-codes/B14000
606   $aMedical Microbiology$3https://scigraph.springernature.com/ontologies/product-market-codes/B16003
606   $aBiochemistry, general$3https://scigraph.springernature.com/ontologies/product-market-codes/L14005
615  0$aImmunology.
615  0$aMedical microbiology.
615  0$aBiochemistry.
615 14$aImmunology.
615 24$aMedical Microbiology.
615 24$aBiochemistry, general.
676   $a572.69
702   $aHsieh$b Shie-Liang$4edt$4http://id.loc.gov/vocabulary/relators/edt
801  0$bMiAaPQ
801  1$bMiAaPQ
801  2$bMiAaPQ
906   $aBOOK
912   $a9910409683603321
996   $aLectin in Host Defense Against Microbial Infections$92531817
997   $aUNINA