LEADER 03695nam 22006375 450 001 9910407724503321 005 20220523101136.0 010 $a3-030-21657-8 024 7 $a10.1007/978-3-030-21657-3 035 $a(CKB)5310000000016667 035 $a(MiAaPQ)EBC6229439 035 $a(DE-He213)978-3-030-21657-3 035 $a(PPN)24859740X 035 $a(EXLCZ)995310000000016667 100 $a20200615d2020 u| 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aGenomics of Pain and Co-Morbid Symptoms$b[electronic resource] /$fedited by Susan G. Dorsey, Angela R. Starkweather 205 $a1st ed. 2020. 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2020. 215 $a1 online resource (254 pages) 311 $a3-030-21656-X 327 $aChapter 1. Pain physiology (defining acute and chronic pain) -- Chapter 2. Neurobiology of nociception (anatomy of ascending and descending systems) -- Chapter 3. Genetics of pain and co-occuring symptoms -- Chapter 4. Sex differences and pain genomics -- Chapter 5. Systems biology/multi-omis approaches to pain and co-occuring symptoms -- Chapter 6. Pre-clinical rodent models of pain for genomics studies -- Chapter 7. Clinical models of experimental pain for genomics studies -- Chapter 8. Clinical pain genomics research -- Chapter 9. Pain phenotyping (methods, measures) -- Chapter 10. Precision health and pain genomics -- Chapter 11. Exemplars of pain genomics studies (could be multiple chapters) -- Chapter 12. Roadmap to translation of pain genomics. 330 $aThis book provides an overview of the field of pain genomics and the genomics of related, or co-occuring, symptoms, the current state-of-the-science, and challenges that remain. It brings differing views in the field together and provides examples of translational science from using cellular and rodent models to human clinical trials. This book's structure leads the reader through the physiology of pain and genomics into how pain is studied, mechanisms of acute and chronic pain, various protocols that are used throughout the field along with the pros/cons of the current methods used, and project into the future of pain genomics. This work is intended for classroom teaching, for nurses, for novice researchers in symptom science and pain research as well as students and postdoctoral fellows. 606 $aNursing?Research 606 $aGenetics 606 $aPain medicine 606 $aNursing Research$3https://scigraph.springernature.com/ontologies/product-market-codes/H41030 606 $aGenetics and Genomics$3https://scigraph.springernature.com/ontologies/product-market-codes/L32000 606 $aPain Medicine$3https://scigraph.springernature.com/ontologies/product-market-codes/H47003 606 $aGenòmica$2thub 606 $aDolor$2thub 606 $aComorbiditat$2thub 608 $aLlibres electrònics$2thub 615 0$aNursing?Research. 615 0$aGenetics. 615 0$aPain medicine. 615 14$aNursing Research. 615 24$aGenetics and Genomics. 615 24$aPain Medicine. 615 7$aGenòmica 615 7$aDolor 615 7$aComorbiditat 676 $a616.0472 702 $aDorsey$b Susan G$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aStarkweather$b Angela R$4edt$4http://id.loc.gov/vocabulary/relators/edt 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910407724503321 996 $aGenomics of Pain and Co-Morbid Symptoms$92201454 997 $aUNINA