LEADER 07301nam 2202065z- 450 001 9910404091203321 005 20210211 010 $a3-03928-539-4 035 $a(CKB)4100000011302226 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/51086 035 $a(oapen)doab51086 035 $a(EXLCZ)994100000011302226 100 $a20202102d2020 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aKidney Inflammation, Injury and Regeneration 210 $cMDPI - Multidisciplinary Digital Publishing Institute$d2020 215 $a1 online resource (496 p.) 311 1 $a3-03928-538-6 330 $aAcute kidney injury (AKI) is still associated with high morbidity and mortality incidence rates, and also bears an elevated risk of subsequent chronic kidney disease. Although the kidney has a remarkable capacity for regeneration after injury and may recover completely depending on the type of renal lesions, the options for clinical intervention are restricted to fluid management and extracorporeal kidney support. The development of novel therapies to prevent AKI, to improve renal regeneration capacity after AKI, and to preserve renal function is urgently needed. The Special Issue covers research articles that investigated the molecular mechanisms of inflammation and injury during different renal pathologies, renal regeneration, diagnostics using new biomarkers, and the effects of different stimuli like medication or bacterial components on isolated renal cells or in vivo models. The Special Issue contains important reviews that consider the current knowledge of cell death and regeneration, inflammation, and the molecular mechanisms of kidney diseases. In addition, the potential of cell-based therapy approaches that use mesenchymal stromal/stem cells or their derivates is summarized. This edition is complemented by reviews that deal with the current data situation on other specific topics like diabetes and diabetic nephropathy or new therapeutic targets. 606 $aMedicine and Nursing$2bicssc 610 $a2-kidney-1-clip 610 $a2k1c 610 $aacute and chronic kidney disease 610 $aacute kidney failure 610 $aacute kidney injury 610 $aAKI 610 $aallograft rejection 610 $aalport syndrome 610 $aapoptosis 610 $aarachidonic acid 610 $aB-cell attracting chemokine 610 $abiomarkers 610 $aC-reactive protein 610 $acAMP Regulatory Element Binding Protein (CREB) 610 $achemerin 610 $achronic kidney disease 610 $achronic kidney disease (CKD) 610 $achronic kidney injury 610 $aClass IIa Histone Deacetylases (HDAC) 610 $aCmklR1 610 $aconditioned medium 610 $acPLA2 and COX-2 610 $aCREB Regulated Transcriptional Coactivators (CRTC) 610 $aCXCL13 610 $acyclooxygenase 610 $acytochrome P450 610 $acytotoxicity 610 $adapagliflozin 610 $adiabetes mellitus 610 $adiabetic kidney disease 610 $adiabetic kidney diseases 610 $adiabetic nephropathy 610 $adiagnostics 610 $adifferentiation 610 $aDSS-colitis 610 $aempagliflozin 610 $aendotoxemia 610 $aendotoxemia-induced oliguric kidney injury 610 $aepithelial cells 610 $aexosome 610 $aexosomes 610 $aextracellular vesicles 610 $aFarnesiferol B 610 $afibrosis 610 $afocal segmental glomerulosclerosis 610 $aG-protein-coupled bile acid receptor (TGR5) 610 $agenotype 610 $aglomerular basement membrane 610 $aglomerular damage 610 $aglomerular filtration barrier (GFB) 610 $aglomerular injury 610 $aglomerulus 610 $aGLP-1 receptor agonists 610 $ahaem 610 $ahematuria 610 $ahypertension 610 $aIgA nephropathy 610 $aIL-18 610 $ainflammation 610 $ainflammatory bowel disease (IBD) 610 $ainflammatory maker 610 $ainjury 610 $ainterleukin-6 610 $aischemia-reperfusion 610 $aischemia/reperfusion injury 610 $akidney 610 $akidney inflammation 610 $akidney injury 610 $akidney proximal tubule 610 $akidney transplantation 610 $aKIT assay 610 $aKIT-IgA score 610 $alipoxygenase 610 $alncRNA 610 $along non-coding RNA 610 $along non-coding RNAs 610 $aLPS-binding protein 610 $alysophosphatidic acid 610 $alysophosphatidic acid receptor 610 $amesenchymal stem cell 610 $amesenchymal stem cells 610 $amesenchymal stromal cells 610 $amesodermal stem cell 610 $amicroRNA 610 $amicroRNAs 610 $amiRNA 610 $amodified-MSCs 610 $amodifier gene 610 $amolecular mechanisms 610 $amolecular signaling 610 $amyofibroblast 610 $an/a 610 $anatural products 610 $anecrosis 610 $anephrin 610 $aniches 610 $aNLRP3 inflammasome 610 $anon-coding RNAs 610 $anoninvasive 610 $aNuclear Factor kappa-light-chain-enhancer of activated B cells (NF-?B) 610 $aobese kidney fibrosis 610 $aomega-3 fatty acid 610 $aoxidative stress 610 $apapilla 610 $apericyte 610 $apigment nephropathy 610 $apodocin 610 $apodocyte 610 $apolymorphism 610 $apolyploidization 610 $apolyunsaturated fatty acids 610 $aprediction 610 $aproximal tubule 610 $aregulated necrosis 610 $arenal cell carcinoma 610 $arenal fibrosis 610 $arenal inflammation 610 $arenal injury 610 $arenal ischemia-reperfusion 610 $arenal progenitors 610 $arenal stem cells 610 $arenal tubular cells 610 $arenovascular hypertension 610 $arhabdomyolysis 610 $aROS 610 $aSalt Inducible Kinase (SIK) 610 $ascattered tubular cells 610 $aSGLT2 inhibitors 610 $asignal transduction 610 $asignaling cascade 610 $aslit diaphragm 610 $astem cell 610 $aT cell-mediated rejection 610 $aTaiwan 610 $atherapeutic target 610 $atherapeutics targets 610 $aThy1.1 nephritis 610 $atranscription 610 $atubular injury 610 $atype I collagen 610 $atype IV collagen 610 $atype V collagen 610 $axanthine oxidase 615 7$aMedicine and Nursing 700 $aKoch$b Benjamin$4auth$01331944 702 $aGeiger$b Helmut$4auth 702 $aBaer$b Patrick C$4auth 906 $aBOOK 912 $a9910404091203321 996 $aKidney Inflammation, Injury and Regeneration$93040686 997 $aUNINA