LEADER 07182nam 2202017z- 450 001 9910404091203321 005 20231214132816.0 010 $a3-03928-539-4 035 $a(CKB)4100000011302226 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/51086 035 $a(EXLCZ)994100000011302226 100 $a20202102d2020 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aKidney Inflammation, Injury and Regeneration 210 $cMDPI - Multidisciplinary Digital Publishing Institute$d2020 215 $a1 electronic resource (496 p.) 311 1 $a3-03928-538-6 330 $aAcute kidney injury (AKI) is still associated with high morbidity and mortality incidence rates, and also bears an elevated risk of subsequent chronic kidney disease. Although the kidney has a remarkable capacity for regeneration after injury and may recover completely depending on the type of renal lesions, the options for clinical intervention are restricted to fluid management and extracorporeal kidney support. The development of novel therapies to prevent AKI, to improve renal regeneration capacity after AKI, and to preserve renal function is urgently needed. The Special Issue covers research articles that investigated the molecular mechanisms of inflammation and injury during different renal pathologies, renal regeneration, diagnostics using new biomarkers, and the effects of different stimuli like medication or bacterial components on isolated renal cells or in vivo models. The Special Issue contains important reviews that consider the current knowledge of cell death and regeneration, inflammation, and the molecular mechanisms of kidney diseases. In addition, the potential of cell-based therapy approaches that use mesenchymal stromal/stem cells or their derivates is summarized. This edition is complemented by reviews that deal with the current data situation on other specific topics like diabetes and diabetic nephropathy or new therapeutic targets. 610 $amicroRNAs 610 $atranscription 610 $aischemia/reperfusion injury 610 $aDSS-colitis 610 $akidney inflammation 610 $atherapeutics targets 610 $aCXCL13 610 $aglomerulus 610 $ainterleukin-6 610 $arhabdomyolysis 610 $aIgA nephropathy 610 $aCREB Regulated Transcriptional Coactivators (CRTC) 610 $aslit diaphragm 610 $ainjury 610 $axanthine oxidase 610 $aSalt Inducible Kinase (SIK) 610 $aacute and chronic kidney disease 610 $atherapeutic target 610 $aKIT-IgA score 610 $aG-protein-coupled bile acid receptor (TGR5) 610 $alysophosphatidic acid 610 $aglomerular injury 610 $aIL-18 610 $amesenchymal stem cells 610 $aTaiwan 610 $aacute kidney injury 610 $arenal ischemia-reperfusion 610 $along non-coding RNA 610 $afibrosis 610 $aacute kidney failure 610 $adiabetic kidney diseases 610 $achronic kidney disease 610 $alncRNA 610 $aLPS-binding protein 610 $aendotoxemia-induced oliguric kidney injury 610 $adapagliflozin 610 $acPLA2 and COX-2 610 $aNLRP3 inflammasome 610 $aCmklR1 610 $ahaem 610 $achronic kidney injury 610 $aomega-3 fatty acid 610 $anoninvasive 610 $ainflammation 610 $aregulated necrosis 610 $aGLP-1 receptor agonists 610 $amiRNA 610 $aAKI 610 $aSGLT2 inhibitors 610 $adiabetic kidney disease 610 $aextracellular vesicles 610 $apodocin 610 $atype IV collagen 610 $aepithelial cells 610 $anephrin 610 $a2-kidney-1-clip 610 $arenal fibrosis 610 $apapilla 610 $adiagnostics 610 $anecrosis 610 $anon-coding RNAs 610 $apodocyte 610 $aThy1.1 nephritis 610 $aKIT assay 610 $aoxidative stress 610 $aconditioned medium 610 $aC-reactive protein 610 $apericyte 610 $amyofibroblast 610 $aNuclear Factor kappa-light-chain-enhancer of activated B cells (NF-?B) 610 $aendotoxemia 610 $amodifier gene 610 $apolymorphism 610 $arenal stem cells 610 $akidney 610 $apolyploidization 610 $aClass IIa Histone Deacetylases (HDAC) 610 $a2k1c 610 $amolecular signaling 610 $aproximal tubule 610 $aarachidonic acid 610 $aempagliflozin 610 $atubular injury 610 $asignaling cascade 610 $asignal transduction 610 $ainflammatory maker 610 $aniches 610 $abiomarkers 610 $arenal progenitors 610 $atype V collagen 610 $acyclooxygenase 610 $afocal segmental glomerulosclerosis 610 $ainflammatory bowel disease (IBD) 610 $achronic kidney disease (CKD) 610 $aallograft rejection 610 $arenovascular hypertension 610 $agenotype 610 $amolecular mechanisms 610 $aROS 610 $aprediction 610 $aglomerular filtration barrier (GFB) 610 $aalport syndrome 610 $ascattered tubular cells 610 $along non-coding RNAs 610 $arenal inflammation 610 $alysophosphatidic acid receptor 610 $acAMP Regulatory Element Binding Protein (CREB) 610 $aFarnesiferol B 610 $adifferentiation 610 $amesenchymal stromal cells 610 $amodified-MSCs 610 $akidney transplantation 610 $apolyunsaturated fatty acids 610 $aapoptosis 610 $atype I collagen 610 $adiabetes mellitus 610 $anatural products 610 $alipoxygenase 610 $astem cell 610 $aT cell-mediated rejection 610 $aexosomes 610 $arenal injury 610 $aobese kidney fibrosis 610 $akidney injury 610 $acytotoxicity 610 $amesenchymal stem cell 610 $apigment nephropathy 610 $amesodermal stem cell 610 $aischemia-reperfusion 610 $acytochrome P450 610 $arenal cell carcinoma 610 $ahematuria 610 $aB-cell attracting chemokine 610 $amicroRNA 610 $achemerin 610 $aglomerular basement membrane 610 $aglomerular damage 610 $arenal tubular cells 610 $akidney proximal tubule 610 $aexosome 610 $ahypertension 610 $adiabetic nephropathy 700 $aKoch$b Benjamin$4auth$01331944 702 $aGeiger$b Helmut$4auth 702 $aBaer$b Patrick C$4auth 906 $aBOOK 912 $a9910404091203321 996 $aKidney Inflammation, Injury and Regeneration$93040686 997 $aUNINA