LEADER 04770nam 2201309z- 450 001 9910404082303321 005 20210211 010 $a3-03928-928-4 035 $a(CKB)4100000011302315 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/42217 035 $a(oapen)doab42217 035 $a(EXLCZ)994100000011302315 100 $a20202102d2020 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aBiological Activities of Alkaloids: From Toxicology to Pharmacology 210 $cMDPI - Multidisciplinary Digital Publishing Institute$d2020 215 $a1 online resource (270 p.) 311 08$a3-03928-927-6 330 $aNatural products are increasingly attracting attention from both basic and applied science. Plant secondary metabolites, especially alkaloids, are receiving interest from a wide range of researchers due to their biological activity. They are produced to protect plants from diseases and herbivores. Therefore, they reveal a toxic activity that affects organisms at various levels of biological organization. A growing amount of research is proving their antimicrobial, antifungal, insecticidal, and anticancer activities. That makes them applicable in various fields from medicine, to pharmacology, veterinary, and toxicology, to crop protection. This Special Issue of Toxins, "Biological Activities of Alkaloids: From Toxicology to Pharmacology"", collects 15 manuscripts describing the ecological, biological, pharmacological, and toxicological effects as well as structural and analytical aspects of plant alkaloids, their mode of action, and possible application in veterinary, medicine, and plant protection. These studies prove the potential for alkaloid application in various areas of science. 517 $aBiological Activities of Alkaloids 606 $aMedicine$2bicssc 610 $a?-carboline 610 $aacetylcholinesterase 610 $aacid-sensing ion channel subtype 1a 610 $aacute toxicity 610 $aalkaloid 610 $aalkaloids 610 $aantibacterial 610 $aanticancer 610 $aantifungal 610 $aantimicrobial activity 610 $aantioxidant 610 $aantiviral 610 $aapoptosis 610 $aApoptosis 610 $aArecoline 610 $abeetles 610 $aberberine 610 $aBerberis thunbergii 610 $abiodistribution 610 $abisbenzylisoquinoline alkaloid 610 $achanoclavine 610 $aChelidonium majus 610 $aCorydalis lutea 610 $aCurine 610 $acytotoxic activity 610 $acytotoxicity 610 $adehydrocrenatidine 610 $adi-ester diterpenoid alkaloids 610 $aDicentra spectabilis 610 $aEGFR 610 $aendophyte 610 $aEpichloe? 610 $aergot alkaloids 610 $aFAK 610 $aFumaria officinalis 610 $aglycoalkaloids 610 $aHPLC-DAD 610 $ainflammation 610 $ainsect 610 $ainsect heart 610 $aisoquinoline alkaloids 610 $aleukemia 610 $alindoldhamine 610 $alipopolysaccharide 610 $alivestock 610 $alung cancer cells 610 $amAchR3 610 $aMacleaya cordata 610 $amacrophage 610 $aMahonia aquifolia 610 $amalonyl-solamargine 610 $amalonylated form 610 $aMeconopsis cambrica 610 $amono-ester diterpenoid alkaloids 610 $an/a 610 $anatural products 610 $anatural sources 610 $aneuropathic pain 610 $aneutrophil 610 $anociception 610 $aOvarian cancer 610 $aPalmatine 610 $aplant secondary metabolites 610 $aRadix Aconiti Lateralis preparations 610 $areproduction 610 $aRutidea parviflora 610 $asanguinarine 610 $asecondary metabolites 610 $ashort-term and long-term usage 610 $asolamargine 610 $aSolanum melongena L. 610 $asolasonine 610 $aSRC 610 $aStaphylococcus aureus 610 $asubchronic feeding study 610 $aTenebrio molitor 610 $atoxicology 610 $avoltage-gated sodium channels 615 7$aMedicine 700 $aAdamski$b Zbigniew$4auth$01331943 702 $aBlythe$b Linda L$4auth 702 $aBufo$b Sabino Aurelio$4auth 702 $aMilella$b Luigi$4auth 906 $aBOOK 912 $a9910404082303321 996 $aBiological Activities of Alkaloids: From Toxicology to Pharmacology$93040683 997 $aUNINA