LEADER 04053nam 22006375 450 001 9910373919403321 005 20240119160741.0 010 $a981-13-9435-0 024 7 $a10.1007/978-981-13-9435-5 035 $a(CKB)4100000009837020 035 $a(DE-He213)978-981-13-9435-5 035 $a(MiAaPQ)EBC5974941 035 $a(PPN)260303542 035 $a(EXLCZ)994100000009837020 100 $a20191106d2019 u| 0 101 0 $aeng 135 $aurnn#008mamaa 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aRecent Trends in Human and Animal Mycology /$fedited by Karuna Singh, Neelabh Srivastava 205 $a1st ed. 2019. 210 1$aSingapore :$cSpringer Singapore :$cImprint: Springer,$d2019. 215 $a1 online resource (XVII, 280 p. 81 illus., 51 illus. in color.) 311 $a981-13-9434-2 327 $aPart I Human and Animal Mycoses -- Pythiosis -- Superficial Mycoses in Dogs and Cats -- Pathogenic Chrysosporium-related Fungi in Reptiles and Other Animals -- Aspergillosis in Humans and Animals -- Some Clinically Significant Genera of Dematiaceous Hyphomycetes: An Update -- Endemic Mycoses in Americas -- Part II Mycotoxins in Relation to Human and Animal Health -- Mycotoxins and Their Inhalatory Intake Risk -- Tenuazonic acid:A Potent Mycotoxin -- Part III Antifungal Therapeutic Candidates -- Phytochemicals: New Avenues in Anti-Candidal Activity -- Recent Advances in Coumarins as Antifungal Agents. 330 $aFungal pathogens pose an on-going and serious threat for poikilotherms and homeotherms, and can cause a broad spectrum of diseases ranging from innocuous to life-threatening. In addition, long-term exposure to some mycotoxigenic moulds can lead to mycotoxicoses in human and animals. Given the expanding population of immune compromised hosts, the list of fungal opportunists grows longer every year. Moreover, antifungal resistance, drug-related toxicity and our limited arsenal of antifungals have exacerbated the situation. To address these problems, strategies such as the identification of novel targets, use of the structure-activity relationship in rational drug design, development of new formulations, modification of existing antifungals to combat resistance, and bioavailability enhancement are called for. For the reader?s convenience, this book has been divided into three sections. The first six chapters of Section I provide a timely review of mycoses, from endemic to cosmopolitan and from generalized to specific, while both chapters of Section II focus on risks associated with mycotoxins. In closing, the two chapters of Section III describe potential antifungal leads and drug candidates based on phytochemicals and coumarin scaffold. 606 $aMycology 606 $aAnimal ecology 606 $aMicrobial ecology 606 $aHuman genetics 606 $aMycology$3https://scigraph.springernature.com/ontologies/product-market-codes/L27000 606 $aAnimal Ecology$3https://scigraph.springernature.com/ontologies/product-market-codes/L19015 606 $aMicrobial Ecology$3https://scigraph.springernature.com/ontologies/product-market-codes/L19082 606 $aHuman Genetics$3https://scigraph.springernature.com/ontologies/product-market-codes/B12008 606 $aMicologia$2thub 608 $aLlibres electrònics$2thub 615 0$aMycology. 615 0$aAnimal ecology. 615 0$aMicrobial ecology. 615 0$aHuman genetics. 615 14$aMycology. 615 24$aAnimal Ecology. 615 24$aMicrobial Ecology. 615 24$aHuman Genetics. 615 7$aMicologia 676 $a579.135 702 $aSingh$b Karuna$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aSrivastava$b Neelabh$4edt$4http://id.loc.gov/vocabulary/relators/edt 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910373919403321 996 $aRecent Trends in Human and Animal Mycology$92020964 997 $aUNINA