LEADER 03620nam 22006135 450 001 9910373917403321 005 20220309160849.0 010 $a981-15-0606-X 024 7 $a10.1007/978-981-15-0606-2 035 $a(CKB)4100000009844716 035 $a(DE-He213)978-981-15-0606-2 035 $a(MiAaPQ)EBC5978936 035 $a(PPN)257359761 035 $a(EXLCZ)994100000009844716 100 $a20191114d2019 u| 0 101 0 $aeng 135 $aurnn#008mamaa 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aAutophagy Regulation of Innate Immunity /$fedited by Jun Cui 205 $a1st ed. 2019. 210 1$aSingapore :$cSpringer Singapore :$cImprint: Springer,$d2019. 215 $a1 online resource (IX, 203 p. 20 illus., 19 illus. in color.) 225 1 $aAdvances in Experimental Medicine and Biology,$x0065-2598 ;$v1209 311 $a981-15-0605-1 320 $aIncludes bibliographical references. 327 $aIntroduction -- Autophagy Regulation of Mammalian Immune Cells -- Autophagy in Plant Immunity -- Autophagy Regulation of Bacterial Pathogen Invasion -- Autophagy and viral infection -- The Interplay between Pattern Recognition Receptors and Autophagy in Inflammation -- Regulation of Inflammasome by Autophagy -- The Cross-regulation between Autophagy and Type I Interferon Signaling in Host Defense -- Selective Autophagy Regulates Innate Immunity through Cargo Receptor Network -- Autophagy and Immune-related Diseases -- Targeting Autophagy with Small-molecule Modulators in Immune-related diseases. 330 $aThis book discusses novel concepts and discoveries concerning the regulation of innate immunity by autophagy and autophagy-related proteins. In the past decade, there have been major advances in our understanding of the molecular mechanisms of autophagy and its physiological functions. This book highlights emerging studies on the underlying mechanisms of autophagy regulation of innate immunity, including inflammation, antiviral immunity and anti-bacterial responses and the signaling pathways that prompt or inhibit the initiation and progression of related diseases. It also offers new ideas and strategies for future drugs based on manipulating autophagy, especially selective autophagy mediated by cargo receptors. Providing a comprehensive overview of the autophagy regulation of innate immunity, it is a valuable resource for graduate students and researchers in the fields of immunology, cell biology and translational medicine. 410 0$aAdvances in Experimental Medicine and Biology,$x0065-2598 ;$v1209 606 $aImmunology 606 $aCytology 606 $aMolecular biology 606 $aImmunologia$2thub 606 $aImmunology$3https://scigraph.springernature.com/ontologies/product-market-codes/B14000 606 $aCell Biology$3https://scigraph.springernature.com/ontologies/product-market-codes/L16008 606 $aMolecular Medicine$3https://scigraph.springernature.com/ontologies/product-market-codes/B1700X 608 $aLlibres electrònics$2thub 615 0$aImmunology. 615 0$aCytology. 615 0$aMolecular biology. 615 7$aImmunologia 615 14$aImmunology. 615 24$aCell Biology. 615 24$aMolecular Medicine. 676 $a616.079 702 $aCui$b Jun$4edt$4http://id.loc.gov/vocabulary/relators/edt 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910373917403321 996 $aAutophagy Regulation of Innate Immunity$92020961 997 $aUNINA