LEADER 05310nam 22007815 450 001 9910373913203321 005 20220601175049.0 010 $a3-030-24100-9 024 7 $a10.1007/978-3-030-24100-1 035 $a(CKB)4100000009845266 035 $a(DE-He213)978-3-030-24100-1 035 $a(MiAaPQ)EBC5977068 035 $a(PPN)257359710 035 $a(EXLCZ)994100000009845266 100 $a20191111d2019 u| 0 101 0 $aeng 135 $aurnn#008mamaa 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aTranslational Research and Onco-Omics Applications in the Era of Cancer Personal Genomics /$fedited by Erika Ruiz-Garcia, Horacio Astudillo-de la Vega 205 $a1st ed. 2019. 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2019. 215 $a1 online resource (X, 171 p. 19 illus. in color.) 225 1 $aAdvances in Experimental Medicine and Biology,$x0065-2598 ;$v1168 311 $a3-030-24099-1 327 $aPreface -- Pharmaco-Geno-Proteo-Metabolomics and Translational Research in Cancer -- Next generation sequencing (NGS): a revolutionary technology in pharmacogenomics and personalized medicine in Cancer -- Pharmaco-epigenomics: on the road of translation medicine -- Design and Implementing Pharmacogenomics Study in Cancer -- Onco-omics approaches and applications in Clinical Trials for Cancer patients -- Issues and Ethical Considerations in Pharmaco-oncogenomics -- Pharma-oncogenomics in the era of personal genomics: a quick guide to online resources and tools -- Inmuno-Oncology in the era of Personalized Medicine -- CAR T Cell and Personalized Medicine -- Oncobiome at the forefront of a novel molecular mechanism to understand the Microbiome and Cancer -- Nutrition, Cancer and Personalized Medicine -- Index. 330 $aThis book presents concise chapters written by internationally respected experts on various important aspects of translational cancer genomics, offering a comprehensive overview of the onco-omics applications in the new era of cancer personal genomics research field. Being a complex disease that affects millions of people worldwide, cancer research has assumed great significance. Translational cancer research transforms scientific discoveries in the laboratory into clinical application to reduce incidence of cancer, morbidity and mortality. In the other hand, personalized medicine in cancer is the concept that selection of a treatment should be tailored according to the individual patient?s specific genomic characteristics, including mutations, chromosomal aberrations, protein interactions, and even more, considering the immune system, the metabolism and in the near future the microbiome, all areas nowadays related in the prognosis and treatment of cancer patients. These contributions are either critical reviews or clinical and basic research reports. The topics discussed here include evidence-based medicine and provides useful information on translational cancer research to clinicians and biomedical scientists in order to offer another vision of cancer origin beyond the traditional causes or the oncogenic maintenance concept proposed by the oncogene addiction theory. 410 0$aAdvances in Experimental Medicine and Biology,$x0065-2598 ;$v1168 606 $aMolecular biology 606 $aCancer research 606 $aPharmaceutical technology 606 $aImmunology 606 $aBiomedical engineering 606 $aGenetics 606 $aMolecular Medicine$3https://scigraph.springernature.com/ontologies/product-market-codes/B1700X 606 $aCancer Research$3https://scigraph.springernature.com/ontologies/product-market-codes/B11001 606 $aPharmaceutical Sciences/Technology$3https://scigraph.springernature.com/ontologies/product-market-codes/B21010 606 $aImmunology$3https://scigraph.springernature.com/ontologies/product-market-codes/B14000 606 $aBiomedical Engineering/Biotechnology$3https://scigraph.springernature.com/ontologies/product-market-codes/B24000 606 $aGenetics and Genomics$3https://scigraph.springernature.com/ontologies/product-market-codes/L32000 606 $aMedicina personalitzada$2thub 606 $aCāncer$2thub 608 $aLlibres electrōnics$2thub 615 0$aMolecular biology. 615 0$aCancer research. 615 0$aPharmaceutical technology. 615 0$aImmunology. 615 0$aBiomedical engineering. 615 0$aGenetics. 615 14$aMolecular Medicine. 615 24$aCancer Research. 615 24$aPharmaceutical Sciences/Technology. 615 24$aImmunology. 615 24$aBiomedical Engineering/Biotechnology. 615 24$aGenetics and Genomics. 615 7$aMedicina personalitzada 615 7$aCāncer 676 $a611.01816 702 $aRuiz-Garcia$b Erika$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aAstudillo-de la Vega$b Horacio$4edt$4http://id.loc.gov/vocabulary/relators/edt 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910373913203321 996 $aTranslational Research and Onco-Omics Applications in the Era of Cancer Personal Genomics$92140617 997 $aUNINA