LEADER 03729nam 22006615 450 001 9910373910303321 005 20220316195023.0 010 $a3-030-27371-7 024 7 $a10.1007/978-3-030-27371-2 035 $a(CKB)4100000009939776 035 $a(MiAaPQ)EBC5987229 035 $a(DE-He213)978-3-030-27371-2 035 $a(PPN)248603434 035 $a(EXLCZ)994100000009939776 100 $a20191127d2019 u| 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aGenetic Causes of Cardiac Disease /$fedited by Jeanette Erdmann, Alessandra Moretti 205 $a1st ed. 2019. 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2019. 215 $a1 online resource (407 pages) $cillustrations 225 1 $aCardiac and Vascular Biology,$x2509-7830 ;$v7 311 $a3-030-27370-9 327 $aGenetics of adult and fetal forms of Long QT Syndrome -- The genetic landscape of cardiomyopathies. Genetic basis of mitochondrial cardiomyopathy -- The Genetics of Coronary Heart Disease -- Complex genetics and the etiology of human congenital heart disease-Familial Hypercholesterolemia -- Long non-codingRNAs in cardiovascular disease -- Mouse models to study inherited cardiomyopathy -- Interrogating cardiovascular genetics in zebrafish -- Human induced pluripotent stem cells as a platform for functional examination of cardiovascular genetics in a dish -- Systems medicine as a transforming tool for cardiovascular genetics -- Sex differences in prevalent cardiovascular disease in the general population. 330 $aThis book provides a comprehensive summary of the latest developments in the field of the genomics of cardiac disease. Written and edited by leading clinicians and scientists involved in the analysis and therapy of genetic cardiac disorders, it discusses the genetic causes of a variety of cardiac diseases, such as the complex genetics and etiology of congenital heart diseases. It also explores sex differences in prevalent diseases, genetics-based therapeutic strategies and the use of various animal models and alternatives. The book is intended for research scientists and clinical scientists in the cardiovascular field, human geneticists and cardiologists. 410 0$aCardiac and Vascular Biology,$x2509-7830 ;$v7 606 $aHuman physiology 606 $aHuman genetics 606 $aCardiology 606 $aAnimal models in research 606 $aHuman Physiology$3https://scigraph.springernature.com/ontologies/product-market-codes/B13004 606 $aHuman Genetics$3https://scigraph.springernature.com/ontologies/product-market-codes/B12008 606 $aCardiology$3https://scigraph.springernature.com/ontologies/product-market-codes/H33037 606 $aAnimal Models$3https://scigraph.springernature.com/ontologies/product-market-codes/L25050 606 $aMalalties cardiovasculars$2thub 608 $aLlibres electrònics$2thub 615 0$aHuman physiology. 615 0$aHuman genetics. 615 0$aCardiology. 615 0$aAnimal models in research. 615 14$aHuman Physiology. 615 24$aHuman Genetics. 615 24$aCardiology. 615 24$aAnimal Models. 615 7$aMalalties cardiovasculars 676 $a616.12042 702 $aErdmann$b Jeanette$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aMoretti$b Alessandra$4edt$4http://id.loc.gov/vocabulary/relators/edt 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910373910303321 996 $aGenetic Causes of Cardiac Disease$91948516 997 $aUNINA