LEADER 03851nam 22006255 450 001 9910373909803321 005 20220601184309.0 010 $a3-030-24517-9 024 7 $a10.1007/978-3-030-24517-7 035 $a(CKB)4100000009939786 035 $a(DE-He213)978-3-030-24517-7 035 $a(MiAaPQ)EBC6022974 035 $a(PPN)242819907 035 $a(EXLCZ)994100000009939786 100 $a20191202d2019 u| 0 101 0 $aeng 135 $aurnn#008mamaa 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aTissue Engineering in Oral and Maxillofacial Surgery /$fedited by Riitta Seppänen-Kaijansinkko 205 $a1st ed. 2019. 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2019. 215 $a1 online resource (VII, 169 p. 55 illus., 52 illus. in color.) 311 $a3-030-24516-0 327 $aIntroduction to Tissue Engineering -- Biomaterials for cranio-maxillo-facial bone engineering -- Cells -- Physical stimulation in tissue engineering -- Growth factors -- Tissue Engineering of Composite Soft Tissue Grafts for Craniomaxillofacial Reconstruction -- Hard tissue engineering -- Vascularization in Oral and Maxillofacial Tissue Engineering -- 3-D Computer Aided Design and Manufacturing -- Safety, Efficacy and Regulation of Mesenchymal Stromal/Stem Cells -- Future perspectives - with special emphasis on extracellular vesicles. 330 $aThis book provides a thorough, up-to-date description of the scientific basis and concepts of tissue engineering in the oral and maxillofacial region. The opening chapters present an introduction to tissue engineering, describe the roles of biomaterials and stem cells, discuss the use of growth factors, and examine potential adverse reactions. The challenges of soft and hard tissue engineering for oral and maxillofacial reconstruction are then considered in detail. It is explained what has been achieved to date, and potential future perspectives are explored. The importance and the verification of adequate vascularization are discussed, and a further focus is the use of 3D printing, both in the planning and production of scaffolds and in the bioprinting of cells and biomaterials. Information is also included on safety, efficacy, and regulatory aspects. Tissue Engineering in Oral and Maxillofacial Surgery will be of interest to all researchers and practitioners who wish to learn more about the potential of tissue engineering to revolutionize practice in oral and maxillofacial surgery. . 606 $aRegenerative medicine 606 $aTissue engineering 606 $aOral surgery 606 $aMaxillofacial surgery 606 $aDentistry 606 $aRegenerative Medicine/Tissue Engineering$3https://scigraph.springernature.com/ontologies/product-market-codes/L16080 606 $aOral and Maxillofacial Surgery$3https://scigraph.springernature.com/ontologies/product-market-codes/H59060 606 $aDentistry$3https://scigraph.springernature.com/ontologies/product-market-codes/D00009 606 $aCirurgia maxil·lofacial$2thub 608 $aLlibres electrònics$2thub 615 0$aRegenerative medicine. 615 0$aTissue engineering. 615 0$aOral surgery. 615 0$aMaxillofacial surgery. 615 0$aDentistry. 615 14$aRegenerative Medicine/Tissue Engineering. 615 24$aOral and Maxillofacial Surgery. 615 24$aDentistry. 615 7$aCirurgia maxil·lofacial 676 $a610.28 702 $aSeppänen-Kaijansinkko$b Riitta$4edt$4http://id.loc.gov/vocabulary/relators/edt 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910373909803321 996 $aTissue Engineering in Oral and Maxillofacial Surgery$92184171 997 $aUNINA