LEADER 04255nam 22007095 450 001 9910373909403321 005 20250609112127.0 010 $a3-030-29108-1 024 7 $a10.1007/978-3-030-29108-2 035 $a(CKB)4100000009939792 035 $a(MiAaPQ)EBC5988111 035 $a(DE-He213)978-3-030-29108-2 035 $a(PPN)258064781 035 $a(MiAaPQ)EBC5988094 035 $a(EXLCZ)994100000009939792 100 $a20191130d2019 u| 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aHIV and Tuberculosis $eA Formidable Alliance /$fedited by Irini Sereti, Gregory P. Bisson, Graeme Meintjes 205 $a1st ed. 2019. 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2019. 215 $a1 online resource (347 pages) $cillustrations 300 $aIncludes index. 311 08$a3-030-29107-3 327 $a1. Overview of the HIV-associated tuberculosis epidemic -- 2 . Epidemiology of Drug-susceptible, Drug-resistant Tuberculosis and HIV in Africa -- 3. Modelling the HIV-associated TB epidemic and the impact of interventions aimed at epidemic control -- 4. Immune responses to Mycobacterium tuberculosis and the impact of HIV infection -- 5. Clinical Manifestations of HIV-associated tuberculosis in adults -- 6. The tuberculosis-associated immune reconstitution inflammatory syndrome (TB-IRIS) -- 7. Diagnosis of HIV-associated tuberculosis -- 8. Recent advances in the treatment of latent tuberculosis infection among adults living with HIV -- 9. Treatment of drug-sensitive tuberculosis in persons with HIV -- 10. Drug-resistant TB and HIV -- 11. Co-treatment of tuberculosis and HIV: pharmacologic considerations -- 12. HIV and TB in children -- 13. Neurological TB in HIV. 330 $aGlobally, HIV-associated tuberculosis is one of the most important causes of infection-related death, accounting for over 300,000 deaths worldwide in 2017. The HIV epidemic has undermined TB control efforts in many countries across the world, as the virus has important modifying effects on the pathogenesis, diagnosis, and treatment of TB. The management of HIV-associated TB is also complicated by rapid clinical progression, immune reconstitution inflammatory syndrome, drug-drug interactions, and shared toxicities. The past two decades have yielded thousands of research publications and review articles on HIV-associated TB. HIV and Tuberculosis: A Formidable Alliance consolidates this massive amount of data into a single resource. With contributions from myriad disciplines, including epidemiology, immunology, public health, and clinical medicine, this book provides well-rounded and thorough coverage that will appeal to researchers and clinicians alike. 606 $aVirology 606 $aInfectious diseases 606 $aImmunology 606 $aEpidemiology 606 $aVirology$3https://scigraph.springernature.com/ontologies/product-market-codes/B22003 606 $aInfectious Diseases$3https://scigraph.springernature.com/ontologies/product-market-codes/H33096 606 $aImmunology$3https://scigraph.springernature.com/ontologies/product-market-codes/B14000 606 $aEpidemiology$3https://scigraph.springernature.com/ontologies/product-market-codes/H63000 606 $aInfeccions per VIH$2thub 606 $aTuberculosi$2thub 608 $aLlibres electrònics$2thub 615 0$aVirology. 615 0$aInfectious diseases. 615 0$aImmunology. 615 0$aEpidemiology. 615 14$aVirology. 615 24$aInfectious Diseases. 615 24$aImmunology. 615 24$aEpidemiology. 615 7$aInfeccions per VIH 615 7$aTuberculosi. 676 $a616.995 676 $a616.9792 702 $aSereti$b Irini$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aBisson$b Gregory P.$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aMeintjes$b Graeme$4edt$4http://id.loc.gov/vocabulary/relators/edt 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910373909403321 996 $aHIV and Tuberculosis$91994033 997 $aUNINA