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010   $a3-030-31434-0
024 7 $a10.1007/978-3-030-31434-7
035   $a(CKB)4100000010011874
035   $a(MiAaPQ)EBC5990233
035   $a(DE-He213)978-3-030-31434-7
035   $a(PPN)242818722
035   $a(EXLCZ)994100000010011874
100   $a20191206d2019      u|         0
101 0 $aeng
135   $aurcnu||||||||
181   $ctxt$2rdacontent
182   $cc$2rdamedia
183   $acr$2rdacarrier
200 14$aThe Biology of mRNA: Structure and Function /$fedited by Marlene Oeffinger, Daniel Zenklusen
205   $a1st ed. 2019.
210  1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2019.
215   $a1 online resource (318 pages)
225 1 $aAdvances in Experimental Medicine and Biology,$x2214-8019 ;$v1203
311   $a3-030-31433-2 
327   $aRegulation of co-transcriptional mRNP assembly -- mRNA export through the NPC -- Roles of mRNA modifications in gene regulation -- Studying mRNPs using single molecule approaches -- Difference between mRNPs and lncRNAs? -- RNPs and/or sequence motives in mRNA localization -- mRNP structure -- New RNA binding proteins: mRNP composition -- Aggregation of repeats RNAs in neurodegenerative diseases -- mRNA structural organization and translation -- How to decide to make an mRNA - degradation -- Methods to study mRNP composition -- mRNA-DNA kisses ? R-loops -- Forms of mRNA editing and their role in disease.
330   $aThe book provides an overview on the different aspects of gene regulation from an mRNA centric viewpoint, including how mRNA is assembled and self-assembles in a complex consisting of RNA and proteins, and how its ability to be translated at the right time and space depends on many processes acting on the mRNAs, leading to a properly folded complex. This book shows how new technologies have led to a better understanding of these processes and their connected diseases. The book is written for scientists in fundamental and applied biomedical research working on different aspects of gene regulation. It is also targeted to an audience that is not implicated in these fields directly, but wants to gain a better understanding of mRNA biology.
410  0$aAdvances in Experimental Medicine and Biology,$x2214-8019 ;$v1203
606   $aMedicine?Research
606   $aBiology?Research
606   $aMolecular genetics
606   $aProteins
606   $aNeurosciences
606   $aPost-translational modification
606   $aBiomedical Research
606   $aMolecular Genetics
606   $aProtein Biochemistry
606   $aNeuroscience
606   $aPost-translational Modifications
606   $aRNA$2thub
608   $aLlibres electrònics$2thub
615  0$aMedicine?Research.
615  0$aBiology?Research.
615  0$aMolecular genetics.
615  0$aProteins.
615  0$aNeurosciences.
615  0$aPost-translational modification.
615 14$aBiomedical Research.
615 24$aMolecular Genetics.
615 24$aProtein Biochemistry.
615 24$aNeuroscience.
615 24$aPost-translational Modifications.
615  7$aRNA
676   $a572.88
676   $a572.88
702   $aOeffinger$b Marlene$4edt$4http://id.loc.gov/vocabulary/relators/edt
702   $aZenklusen$b Daniel$4edt$4http://id.loc.gov/vocabulary/relators/edt
801  0$bMiAaPQ
801  1$bMiAaPQ
801  2$bMiAaPQ
906   $aBOOK
912   $a9910373908303321
996   $aThe Biology of mRNA: Structure and Function$92115744
997   $aUNINA