LEADER 05097nam 2201273z- 450 001 9910372786403321 005 20210211 010 $a3-03921-991-X 035 $a(CKB)4100000010163762 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/54960 035 $a(oapen)doab54960 035 $a(EXLCZ)994100000010163762 100 $a20202102d2020 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aNutrition and Eye Health 210 $cMDPI - Multidisciplinary Digital Publishing Institute$d2020 215 $a1 online resource (242 p.) 311 08$a3-03921-990-1 330 $aBlindness and visual impairment impact significantly on an individual's physical and mental well-being. Loss of vision is a global health problem, with approximately 250 million of the world's population currently living with vision loss, of which 36 million are classified as blind. Visual impairment is more frequent in the elderly, with cataract and age-related macular degeneration (AMD) accounting for over 50% of cases globally. Oxidative stress has been strongly implicated in the pathogenesis of both conditions, and consequently the role of nutritional factors, in particular carotenoids and micronutrient antioxidants, have been investigated as possible preventative or therapeutic strategies. Dry eye syndrome (DES) is one of the most common ophthalmic conditions in the world. DES occurs where the eye does not produce enough tears and/or the tears evaporate too quicklyleading to discomfort and varying degrees of visual disturbance. There has recently been a great deal of interest in the potential for oral or topical supplementation with essential fatty acids (EFAs), specifically omega-3 and omega-6 fatty acids, as an adjunct to conventional treatments for DES. The objective of this Special Issue on 'Nutrition and Eye Health' is to publish papers describing the role of nutrition in maintaining eye health and the use of nutritional interventions to prevent or treat ocular disease. A particular (but not exclusive) emphasis will be on papers (reviews and/or clinical or experimental studies) relating to cataract, AMD and DES. 606 $aBiology, life sciences$2bicssc 610 $aadvanced glycation end products 610 $aage-related macular degeneration 610 $aAGREE II 610 $aAMD 610 $aangiogenesis 610 $aanti-inflammatory 610 $aanti-oxidant 610 $aantioxidant supplements 610 $acarotenoids 610 $acataract 610 $achyrsin 610 $aclinical practice guidelines 610 $aclinical survey 610 $aCODS 610 $acorneal chemical burn 610 $acorneal neovascularization (CNV) 610 $acrocetin 610 $acrocin 610 $aCrocus Sativus L. 610 $aCucurbita argyrosperma 610 $acyclooxigenase-2 (COX-2) 610 $adiabetes 610 $adiabetic retinopathy 610 $adiet 610 $adietary antioxidants 610 $adietary assessment 610 $adietary habits 610 $adrug discovery 610 $adry eye 610 $aelectroretinography 610 $aendoplasmic reticulum 610 $aendoplasmic reticulum stress 610 $aestrogen-deficient rats 610 $aeye disease 610 $afatty acid 610 $afish oil 610 $aflavonoids 610 $afood frequency questionnaire 610 $aglaucoma 610 $agut microbiota 610 $agut-retina axis 610 $ainflammation 610 $ainterleukin-1? (IL-1?) 610 $aLactobacillus paracasei KW3110 610 $alens 610 $alenses 610 $alight 610 $alight damage 610 $alutein 610 $amacrophage 610 $amesozeaxanthin (RS zeaxanthin) 610 $amicronutrients 610 $amicrovascular lesions 610 $an/a 610 $aneoangiogenesis 610 $anuclear factor-kappaB (NF-?B) 610 $anutrition 610 $anutritional supplements 610 $aomega-3 610 $aomega-3 polyunsaturated fatty acids 610 $aoxidative stress 610 $apersonalised medicine 610 $aphotoreceptor degeneration 610 $aphytoconstituents 610 $apolyphenols 610 $apreclinical models 610 $areduced glutathione 610 $aretina 610 $aretinal pigment epithelium 610 $arosmarinic acid 610 $aRR-zeaxanthin 610 $asaffron 610 $asaponins 610 $asinapic acid 610 $asupplements 610 $asystematic reviews 610 $avascular endothelial growth factor (VEGF) 610 $avisual cycle 615 7$aBiology, life sciences 700 $aDownie$b Laura$4auth$01301184 702 $aLawrenson$b John$4auth 906 $aBOOK 912 $a9910372786403321 996 $aNutrition and Eye Health$93025773 997 $aUNINA