LEADER 03172nam 22005295 450 001 9910369932803321 005 20200629125313.0 010 $a3-030-18626-1 024 7 $a10.1007/978-3-030-18626-5 035 $a(CKB)4100000009273676 035 $a(DE-He213)978-3-030-18626-5 035 $a(MiAaPQ)EBC5898192 035 $a(PPN)248600893 035 $a(EXLCZ)994100000009273676 100 $a20190917d2020 u| 0 101 0 $aeng 135 $aurnn|008mamaa 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aPersonalized and Precision Medicine Informatics $eA Workflow-Based View /$fedited by Terrence Adam, Constantin Aliferis 205 $a1st ed. 2020. 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2020. 215 $a1 online resource (XVI, 349 p. 67 illus., 45 illus. in color.) 225 1 $aHealth Informatics,$x1431-1917 300 $aIncludes index. 311 $a3-030-18625-3 327 $aPersonalized Medicine -- Precision Medicine -- Personalized Health -- Precision Health -- Pharmacogenomics -- Pharmacogenetics -- Clinical Informatics -- Genomic Medicine -- Disease Subtyping -- Tumor sequencing -- Clinical Diagnostics -- Molecular Profiling -- Precision Trials -- Clinical Genomics -- Patient Risk Stratification. 330 $aThis book adopts an integrated and workflow-based treatment of the field of personalized and precision medicine (PPM). Outlined within are established, proven and mature workflows as well as emerging and highly-promising opportunities for development. Each workflow is reviewed in terms of its operation and how they are enabled by a multitude of informatics methods and infrastructures. The book goes on to describe which parts are crucial to discovery and which are essential to delivery and how each of these interface and feed into one-another. Personalized and Precision Medicine Informatics provides a comprehensive review of the integrative as well as interpretive nature of the topic and brings together a large body of literature to define the topic and ensure that this is the key reference for the topic. It is an unique contribution that is positioned to be an essential guide for both PPM experts and non-experts, and for both informatics and non-informatics professionals. 410 0$aHealth Informatics,$x1431-1917 606 $aHealth informatics 606 $aHealth Informatics$3https://scigraph.springernature.com/ontologies/product-market-codes/H28009 606 $aHealth Informatics$3https://scigraph.springernature.com/ontologies/product-market-codes/I23060 615 0$aHealth informatics. 615 14$aHealth Informatics. 615 24$aHealth Informatics. 676 $a502.85 676 $a610.285 702 $aAdam$b Terrence$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aAliferis$b Constantin$4edt$4http://id.loc.gov/vocabulary/relators/edt 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910369932803321 996 $aPersonalized and Precision Medicine Informatics$92263919 997 $aUNINA