LEADER 03356nam 22004815 450 001 9910369932303321 005 20251113195443.0 010 $a3-030-22922-X 024 7 $a10.1007/978-3-030-22922-1 035 $a(CKB)4100000009375060 035 $a(DE-He213)978-3-030-22922-1 035 $a(MiAaPQ)EBC5906297 035 $a(PPN)269146679 035 $a(EXLCZ)994100000009375060 100 $a20190926d2020 u| 0 101 0 $aeng 135 $aurnn#008mamaa 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aGenomic Medicine $eA Practical Guide /$fedited by Laura J. Tafe, Maria E. Arcila 205 $a1st ed. 2020. 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2020. 215 $a1 online resource (X, 325 p. 21 illus., 20 illus. in color.) 300 $aIncludes index. 311 08$a3-030-22921-1 327 $aPre-Analytics, Current Testing Technologies, and Limitations of Testing -- Next Generation Sequencing -- Cell Free DNA Testing -- Role of Bioinformatics in Molecular Medicine -- Interpreting Genomic Reports -- Lung Carcinoma -- GI including GIST -- Breast -- Genitourinary Tumors -- Gynecologic Malignancies -- Sarcomas -- Salivary Gland Carcinomas -- Sinonasal Carcinomas -- Acute Myeloid Neoplasms -- Chronic Myeloid Neoplasms -- Lymphomas. 330 $aThe field of Molecular Diagnostics is rapidly evolving and molecular characterization of neoplasms is becoming an increasingly important part of the pathologic work up and diagnosis of many tumor types. This work provides a high-yield reference book that compiles critical information related to molecular biomarkers for various solid tumor and hematologic malignancy subtypes. It is succinct yet comprehensive enough to be suitable for fellows in training and medical professionals with an interest in molecular pathology and biomarkers. The book covers many aspects of molecular diagnostics, from techniques to applications and comprehensive summaries of the current molecular biomarkers of critical importance in solid and liquid tumors. Attention is also specifi cally devoted to bioinformatics and next generation sequencing, as well as pre-analytical issues that must be considered for accurate interpretation of molecular results in the context of overall patient care. Thistext focuses on clinical utility and validity and serves as an ?owner?s manual? in Genomic Diagnostics for the practicing pathologist, pathology fellows and residents and other health care providers. Physicians will find this book invaluable as a quick reference for current molecular testing modalities and guidelines, tumor board preparation, deciding which test to order and interpreting genomic laboratory results. In addition, it is an accessible for trainees as a board review preparation reference. 606 $aPathology 606 $aPathology 615 0$aPathology. 615 14$aPathology. 676 $a616.07 676 $a616.07 702 $aTafe$b Laura J$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aArcila$b Maria E$4edt$4http://id.loc.gov/vocabulary/relators/edt 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910369932303321 996 $aGenomic medicine$92039924 997 $aUNINA