LEADER 03572nam 2200685 a 450 001 9910459584503321 005 20200520144314.0 010 $a1-283-12029-1 010 $a9786613120298 010 $a90-04-18276-4 024 7 $a10.1163/ej.9789004191723.i-432 035 $a(CKB)2670000000083803 035 $a(EBL)717459 035 $a(OCoLC)727951474 035 $a(SSID)ssj0000502527 035 $a(PQKBManifestationID)12202844 035 $a(PQKBTitleCode)TC0000502527 035 $a(PQKBWorkID)10520852 035 $a(PQKB)11518859 035 $a(MiAaPQ)EBC717459 035 $a(OCoLC)691927880 035 $a(nllekb)BRILL9789004182769 035 $a(PPN)174392737 035 $a(Au-PeEL)EBL717459 035 $a(CaPaEBR)ebr10470519 035 $a(CaONFJC)MIL312029 035 $a(EXLCZ)992670000000083803 100 $a20101129d2011 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aAftermaths of war$b[electronic resource] $ewomen's movements and female activists, 1918-1923 /$fedited by Ingrid Sharp, Matthew Stibbe 210 $aBoston $cBrill$d2011 215 $a1 online resource (454 p.) 225 1 $aHistory of warfare,$x1385-7827 ;$vv. 63 300 $aDescription based upon print version of record. 311 $a90-04-19172-0 320 $aIncludes bibliographical references and index. 327 $apt. 1. Commemoration, remembering, remobilisation -- pt. 2. The renegotiation of gender roles -- pt. 3. Women's suffrage and political rights -- pt. 4. Reconstructing communities/visions of peace. 330 $aMuch of the recent literature on cultural demobilisation or remobilisation after the First World War has focused on men and masculinity. By contrast, this interdisciplinary volume of essays sets out to examine the importance of women?s movements and individual female activists to the shaping of post-war Europe at the private, communal, national and transnational levels. Key themes include the commemoration of the war dead; the renegotiation of gender roles; suffrage and political rights; and women?s contribution to the establishment of new visions of peace or national revenge and regeneration in the years 1918 to 1923. The eighteen chapters cover countries in Central and Eastern Europe, as well as Western Europe, and defeated as well as victorious nations, thus allowing for a more nuanced understanding of the deep impact of the war and its aftermath on the continent as a whole. Contributors are Nikolai Vukov, Emma Schiavon, Christiane Streubel, Erika Kuhlman, Ann Rea, Ingrid Sharp, Olga Shnyrova, Fatmira Musaj and Beryl Nicholson, Christine Bard, Gabriella Hauch, Judith Szapor, Sylwia Ku?ma-Markowska, Virginija Jur?nien?, Judit Acsády, Matthew Stibbe, Bruce Berglund, David Hudson and Jill Liddington. 410 0$aHistory of warfare ;$vv. 63. 606 $aFeminism$zEurope$xHistory$y20th century 606 $aWomen political activists$zEurope$xHistory$y20th century 606 $aWorld War, 1914-1918$xSocial aspects$zEurope 608 $aElectronic books. 615 0$aFeminism$xHistory 615 0$aWomen political activists$xHistory 615 0$aWorld War, 1914-1918$xSocial aspects 676 $a305.42094/09042 701 $aSharp$b Ingrid$0913502 701 $aStibbe$b Matthew$0502288 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910459584503321 996 $aAftermaths of war$92046174 997 $aUNINA LEADER 04950nam 22013333a 450 001 9910367759103321 005 20250203235431.0 010 $a9783039215065 010 $a303921506X 024 8 $a10.3390/books978-3-03921-506-5 035 $a(CKB)4100000010106126 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/61057 035 $a(ScCtBLL)7b6ff77e-eae3-4c7f-86a4-870ff8687741 035 $a(OCoLC)1163832114 035 $a(oapen)doab61057 035 $a(EXLCZ)994100000010106126 100 $a20250203i20192019 uu 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aTowards Mechanism-based Treatments for Fragile X Syndrome$fInbal Gazy, Daman Kumari 210 $cMDPI - Multidisciplinary Digital Publishing Institute$d2019 210 1$aBasel, Switzerland :$cMDPI,$d2019. 215 $a1 electronic resource (250 p.) 311 08$a9783039215058 311 08$a3039215051 330 $aIt has been more than 25 years since the identification of the FMR1 gene and the demonstration of the causative role of CGG-repeat expansion in the disease pathology of fragile X syndrome (FXS), but the underlying mechanisms involved in the expansion mutation and the resulting gene silencing still remain elusive. Our understanding of the pathways impacted by the loss of FMRP function has grown tremendously, and has opened new avenues for targeted treatments for FXS. However, the failure of recent clinical trials that were based on successful preclinical studies using the Fmr1 knockout mouse model has forced the scientific community to revisit clinical trial design and identify objective outcome measures. There has also been a renewed interest in restoring FMR1 gene expression as a possible treatment approach for FXS. This special issue of Brain Sciences highlights the progress that has been made towards understanding the disease mechanisms and how this has informed the development of treatment strategies that are being explored for FXS. 606 $aBiology, life sciences$2bicssc 610 $alymphoblast 610 $apluripotent stem cells 610 $aFMR1 610 $aGene editing 610 $aX chromosome 610 $aFmr1 610 $aepigenetic gene silencing 610 $aFMR1 gene 610 $aFragile X syndrome 1 610 $arepeat instability 610 $acharacteristics that have the greatest impact 610 $aDNA instability 610 $aworking memory 610 $alanguage development 610 $amosaicism 610 $aCRISPR 3 610 $aclinical trials 610 $aautism spectrum disorders 610 $aFmr1 KO mouse 610 $aautomated vocal analysis 610 $abase excision repair (BER) 610 $ainhibitory control 610 $acerebral spinal fluid 610 $aiPSC 610 $adrug development 610 $atargeted treatments 610 $amolecular biomarkers 610 $aviral vector 610 $aavoidance 610 $abiomarker 610 $aset-shifting 610 $aearly identification 610 $aexpansion 610 $aanxiety 610 $aplanning 610 $avoice of the person 610 $amismatch repair (MMR) 610 $agene reactivation 610 $adouble-strand break repair (DSBR) 610 $anewborn screening 610 $aintellectual disability 610 $aprocessing speed 610 $avoice of the patient 610 $afragile X syndrome 610 $aadeno-associated virus 610 $aneurodevelopmental disorders 610 $ahistone methylation 610 $aNon-homologous end-joining (NHEJ) 610 $aASD 610 $aFxr2 610 $aFragile X-associated Tremor/Ataxia Syndrome 2 610 $aTrinucleotide Repeat 4 610 $aCGG Repeat Expansion Disease 610 $aDNA methylation 610 $acontraction 610 $afragile X mental retardation protein 610 $aRNA:DNA hybrid 610 $abehavior 610 $adevelopmental disorders 610 $acognition 610 $afemales 610 $aFMRP 610 $aFragile X Syndrome 610 $aunstable repeat diseases 610 $aprotein synthesis 610 $abrain 610 $acognitive flexibility 610 $atreatment development 610 $afibroblast 610 $aPRC2 610 $atranscription coupled repair (TCR) 610 $abest practices 610 $aattention 610 $aFragile X 610 $aexecutive function 615 7$aBiology, life sciences 700 $aGazy$b Inbal$01786965 702 $aKumari$b Daman 801 0$bScCtBLL 801 1$bScCtBLL 906 $aBOOK 912 $a9910367759103321 996 $aTowards Mechanism-based Treatments for Fragile X Syndrome$94319525 997 $aUNINA LEADER 06156nam 22008415 450 001 9910483365103321 005 20251226202333.0 010 $a1-280-38753-X 010 $a9786613565457 010 $a3-642-13971-X 024 7 $a10.1007/978-3-642-13971-0 035 $a(CKB)2670000000028966 035 $a(SSID)ssj0000446661 035 $a(PQKBManifestationID)11249948 035 $a(PQKBTitleCode)TC0000446661 035 $a(PQKBWorkID)10496712 035 $a(PQKB)11294908 035 $a(DE-He213)978-3-642-13971-0 035 $a(MiAaPQ)EBC3065404 035 $a(PPN)149064209 035 $a(EXLCZ)992670000000028966 100 $a20100616d2010 u| 0 101 0 $aeng 135 $aurnn#008mamaa 181 $ctxt 182 $cc 183 $acr 200 10$aNetworked Services and Applications - Engineering, Control and Management $e16th EUNICE/IFIP WG 6.6 Workshop, EUNICE 2010, Trondheim, Norway, June 28-30, 2010, Proceedings /$fedited by Finn Arve Aagesen, Svein J. Knapskog 205 $a1st ed. 2010. 210 1$aBerlin, Heidelberg :$cSpringer Berlin Heidelberg :$cImprint: Springer,$d2010. 215 $a1 online resource (XIII, 275 p. 125 illus.) 225 1 $aInformation Systems and Applications, incl. Internet/Web, and HCI,$x2946-1642 ;$v6164 300 $aBibliographic Level Mode of Issuance: Monograph 311 08$a3-642-13970-1 327 $aAdmission Control and Networking -- On the Performance of Grooming Strategies for Offloading IP Flows onto Lightpaths in Hybrid Networks -- MBAC: Impact of the Measurement Error on Key Performance Issues -- An Algorithm for Automatic Base Station Placement in Cellular Network Deployment -- An Energy-Efficient FPGA-Based Packet Processing Framework -- Service Mobility -- Service Migration Protocol for NFC Links -- Swarm Intelligence Heuristics for Component Deployment -- Peer-to-Peer and Virtualization -- On Force-Based Placement of Distributed Services within a Substrate Network -- Enabling P2P Gaming with Network Coding -- A Virtual File System Interface for Computational Grids -- Security -- Labeled VoIP Data-Set for Intrusion Detection Evaluation -- Document Provenance in the Cloud: Constraints and Challenges -- Wireless Handoff Optimization: A Comparison of IEEE 802.11r and HOKEY -- Introducing Perfect Forward Secrecy for AN.ON -- Congestion Control -- Mobility-Aware Drop Precedence Scheme in DiffServ-Enabled Mobile Network Systems -- Theoretical Analysis of an Ideal Startup Scheme in Multihomed SCTP -- Monitoring and Filtering -- The Network Data Handling War: MySQL vs. NfDump -- Processing of Flow Accounting Data in Java: Framework Design and Performance Evaluation -- Fighting Spam on the Sender Side: A Lightweight Approach -- Dependability -- Degradation Model for Erbium-Doped Fiber Amplifiers to Reduce Network Downtime -- A Token Based Approach Detecting Downtime in Distributed Application Servers or Network Elements -- Distributed Resource Reservation for Beacon Based MAC Protocols -- Adaptation and Reconfiguration -- On Runtime Adaptation of Application-Layer Multicast Protocol Parameters -- A Framework with Proactive Nodes for Scheduling and Optimizing Distributed Embedded Systems -- Resource Adaptive Distributed Information Sharing -- Poster Session -- Performance Impacts of Node Failures on a Chord-Based Hierarchical Peer-to-Peer Network -- A Low-Power Scheme for Localization in Wireless Sensor Networks -- Flow Aggregation Using Dynamic Packet State -- Evaluating MDC with Incentives in P2PTV Systems -- Translation from UML to SPN Model: A Performance Modeling Framework -- An Open and Extensible Service Discovery for Ubiquitous Communication Systems. 330 $aThe EUNICE (European Network of Universities and Companies in Information and Communication technology) (http://www.eunice-forum.org) mission is to jointly - velop and promote the best and most compatible standard of European higher edu- tion and professionals in ICT by increasing scientific and technical knowledge in the field of ICT and developing their applications in the economy. The EUNICE Wo- shop is an annual event. This year the workshop was sponsored by IFIP TC 6 WG 6.6: Management of Networks and Distributed Systems. Eight years ago, the seventh edition of the EUNICE workshop took place in Tro- heim with the topic ?Adaptable Networks and Teleservices.? Since then ?adaptability? has become a topic which is found in most ICT conferences. The concept teleservices, which is a telecommunication domain concept from the 1980s, has been lifted out of the telecom community and is now found with new and sometimes mysterious names such as service?oriented architecture and cloud computing. 410 0$aInformation Systems and Applications, incl. Internet/Web, and HCI,$x2946-1642 ;$v6164 606 $aComputer networks 606 $aComputer science 606 $aCryptography 606 $aData encryption (Computer science) 606 $aElectronic data processing$xManagement 606 $aAlgorithms 606 $aComputers and civilization 606 $aComputer Communication Networks 606 $aTheory of Computation 606 $aCryptology 606 $aIT Operations 606 $aAlgorithms 606 $aComputers and Society 615 0$aComputer networks. 615 0$aComputer science. 615 0$aCryptography. 615 0$aData encryption (Computer science). 615 0$aElectronic data processing$xManagement. 615 0$aAlgorithms. 615 0$aComputers and civilization. 615 14$aComputer Communication Networks. 615 24$aTheory of Computation. 615 24$aCryptology. 615 24$aIT Operations. 615 24$aAlgorithms. 615 24$aComputers and Society. 676 $a004.6 701 $aAagesen$b Finn Arve$01762200 701 $aKnapskog$b Svein Johan$01752466 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910483365103321 996 $aNetworked services and applications-- engineering, control and management$94201980 997 $aUNINA