LEADER 03091nam 2200709z- 450 001 9910367756503321 005 20231214133048.0 010 $a3-03921-174-9 035 $a(CKB)4100000010106152 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/59280 035 $a(EXLCZ)994100000010106152 100 $a20202102d2019 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aSex Hormone Receptor Signals in Human Malignancies 210 $cMDPI - Multidisciplinary Digital Publishing Institute$d2019 215 $a1 electronic resource (152 p.) 311 $a3-03921-173-0 330 $aSex steroids, including androgens, estrogens, and progestogens, are knownto have widespread physiological actions beyond the reproductive systemvia binding to the sex hormone receptors. Meanwhile, emerging evidence hasindicated that sex hormone receptor signals are involved in the outgrowth ofsome malignancies, such as prostate and breast carcinomas, as well as othersthat have not traditionally been considered as endocrine-related neoplasms. ThisSpecial Issue ?Sex Hormone Receptor Signals in Human Malignancies? coversvarious aspects of the potential role of sex hormone receptors and related signalsin prostate cancer, breast cancer, and other neoplastic conditions by depictingpromising findings derived from in vitro and in vivo experiments as well as theanalyses of surgical specimens. The current observations described may thusprovide a unique insight into novel or known functions of sex hormone receptorsand related molecules. 610 $aFOXA1 610 $aCOBRA1 610 $aestrogen 610 $aprogesterone receptor negative 610 $amutational profiling 610 $aheterogeneous nuclear ribonucleoprotein K 610 $aestrogen receptor alpha 610 $asalivary gland tumors 610 $acastration-resistant prostate cancer 610 $aELK1 610 $afibroblasts 610 $aandrogen receptor 610 $amelanocytes 610 $adrug screening and proteomics 610 $aPI3K pathway 610 $aNELFB 610 $atherapeutic targets 610 $aimmunohistochemistry 610 $aandrogen deprivation therapy 610 $aovarian cancer 610 $aestrogen receptor 610 $aepidermal growth factor receptor 610 $aethinylestradiol 610 $amelanoma 610 $abreast cancer 610 $akeratinocytes 610 $aG-protein coupled estrogen receptor 610 $aprognosis 610 $alevonorgestrel 610 $aultraviolet radiation 610 $asex hormone receptors 610 $aupper urinary tract urothelial carcinoma 610 $aCRPC 610 $anuclear factor erythroid 2-related factor 2 610 $aTP53 700 $aMiyamoto$b Hiroshi$4auth$01297599 906 $aBOOK 912 $a9910367756503321 996 $aSex Hormone Receptor Signals in Human Malignancies$93024598 997 $aUNINA