LEADER 00878nam0-22003131i-450- 001 990000588580403321 005 20001010 035 $a000058858 035 $aFED01000058858 035 $a(Aleph)000058858FED01 035 $a000058858 100 $a20001010d--------km-y0itay50------ba 101 0 $aita 105 $ay-------001yy 200 1 $aSTATIK DER TRAGWERKE$fKAUFMANN WALTHER 210 $aBerlin$cSpringer Verlag$d1949 610 0 $aMateriali da Costruzione 610 0 $aCostruzioni di Macchine 610 0 $aTeoria e pratica delle Costruzioni civili e industriali 610 0 $aMeccanica Razionale 700 1$aKaufmann,$bWalther$028830 801 0$aIT$bUNINA$gRICA$2UNIMARC 901 $aBK 912 $a990000588580403321 952 $a07 B-211$b2639$fDINSC 959 $aDINSC 996 $aSTATIK DER TRAGWERKE$9318241 997 $aUNINA DB $aING01 LEADER 04166nam 22012973a 450 001 9910367750403321 005 20250203235427.0 010 $a9783039214082 010 $a303921408X 024 8 $a10.3390/books978-3-03921-408-2 035 $a(CKB)4100000010106213 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/53845 035 $a(ScCtBLL)db69e1af-5782-4846-81f7-14c2b9141c10 035 $a(OCoLC)1163824875 035 $a(EXLCZ)994100000010106213 100 $a20250203i20192019 uu 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aMolecular Mechanism of Alzheimer's Disease$fIan Macreadie 210 1$aBasel, Switzerland :$cMDPI,$d2019. 215 $a1 electronic resource (228 p.) 311 08$a9783039214075 311 08$a3039214071 330 $aAlzheimer's disease (AD) is an age-related neurological disease that affects tens of millions of people, in addition to their carers. Hallmark features of AD include plaques composed of amyloid beta, as well as neurofibrillary tangles of tau protein. However, despite more than a century of study, the cause of Alzheimer's disease remains unresolved. The roles of amyloid beta and tau are being questioned and other causes of AD are now under consideration. The contributions of researchers, model organisms, and various hypotheses will be examined in this Special Issue. 610 $aHOTAIR 610 $aneurosciences 610 $asleep disturbance 610 $apositron emission tomography (PET) 610 $avitamin B complex 610 $aneurodegeneration 610 $aTau 610 $amiR-15/107 610 $adefault-mode network 610 $acomplement receptor 1 610 $aneuronal differentiation 610 $aepigenetics 610 $abrain glucose metabolism 610 $aoligomerization 610 $agenetic risk 610 $aA?O receptors 610 $aprion 610 $aryanodine receptor 610 $atype 3 diabetes 610 $acomplement 610 $acognitive behavioral therapy for insomnia 610 $acognitive function 610 $aepigenome-wide association study 610 $aAlzheimer?s disease 610 $acalcium signaling 610 $a?-secretase 610 $atau 610 $aProlyl isomerases 610 $aNEAT1 610 $acomplement C3b/C4b receptor 610 $aproteostasis 610 $aamyloid beta 610 $ayeast 610 $aslow-wave sleep 610 $aamyloid ? 610 $anutrition 610 $a4 610 $aprotein aggregation 610 $aapolipoprotein E 610 $adementia 610 $aMALAT1 610 $ainositol 1 610 $alncRNAs 610 $amolecular biology 610 $amethylenetetrahydrofolate reductase MTHFR gene 610 $a5-trisphosphate receptor 610 $aCR1 density 610 $amiR-34c 610 $aaggregation 610 $aheat shock protein 610 $adendritic spine 610 $aS-adenosylmethionine 610 $abeta amyloid 610 $aion channel 610 $ainflammation 610 $asleep fragmentation 610 $acystathionine-?-lyase CTH gene 610 $aDNA methylation 610 $aheat shock response 610 $amicroglia 610 $adrug target discovery 610 $aamyloid-? oligomer 610 $atherapy 610 $aCR1 length polymorphism 610 $amethylome 610 $aAPOE gene 610 $aubiquitin 610 $amagnetic resonance imaging (MRI) 610 $aneuronal degeneration 610 $atype 2 diabetes 610 $aPin1 610 $amild cognitive impairment 610 $adairy products 610 $aendoplasmic reticulum 610 $aoxidative stress 610 $aHispanics 610 $aCDK5R1 700 $aMacreadie$b Ian$01325223 801 0$bScCtBLL 801 1$bScCtBLL 906 $aBOOK 912 $a9910367750403321 996 $aMolecular Mechanism of Alzheimer's Disease$93036703 997 $aUNINA