LEADER 05118nam 2200997z- 450 001 9910367739803321 005 20210211 010 $a3-03921-825-5 035 $a(CKB)4100000010106319 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/53381 035 $a(oapen)doab53381 035 $a(EXLCZ)994100000010106319 100 $a20202102d2019 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aMicro/Nano Devices for Blood Analysis 210 $cMDPI - Multidisciplinary Digital Publishing Institute$d2019 215 $a1 online resource (174 p.) 311 08$a3-03921-824-7 330 $aThe development of micro- and nanodevices for blood analysis is an interdisciplinary subject that demands the integration of several research fields, such as biotechnology, medicine, chemistry, informatics, optics, electronics, mechanics, and micro/nanotechnologies. Over the last few decades, there has been a notably fast development in the miniaturization of mechanical microdevices, later known as microelectromechanical systems (MEMS), which combine electrical and mechanical components at a microscale level. The integration of microflow and optical components in MEMS microdevices, as well as the development of micropumps and microvalves, have promoted the interest of several research fields dealing with fluid flow and transport phenomena happening in microscale devices. Microfluidic systems have many advantages over their macroscale counterparts, offering the ability to work with small sample volumes, providing good manipulation and control of samples, decreasing reaction times, and allowing parallel operations in one single step. As a consequence, microdevices offer great potential for the development of portable and point-of-care diagnostic devices, particularly for blood analysis. Moreover, the recent progress in nanotechnology has contributed to its increasing popularity, and has expanded the areas of application of microfluidic devices, including in the manipulation and analysis of flows on the scale of DNA, proteins, and nanoparticles (nanoflows). In this Special Issue, we invited contributions (original research papers, review articles, and brief communications) that focus on the latest advances and challenges in micro- and nanodevices for diagnostics and blood analysis, micro- and nanofluidics, technologies for flow visualization, MEMS, biochips, and lab-on-a-chip devices and their application to research and industry. We hope to provide an opportunity to the engineering and biomedical community to exchange knowledge and information and to bring together researchers who are interested in the general field of MEMS and micro/nanofluidics and, especially, in its applications to biomedical areas. 606 $aTechnology: general issues$2bicssc 610 $abiomedical coatings 610 $abiomicrofluidics 610 $ablood on chips 610 $acancer 610 $aCEA detection 610 $acell adhesion 610 $acell analysis 610 $acell deformability 610 $acentrifugal microfluidic device 610 $achronic renal disease 610 $acircular microchannel 610 $acomputational biomechanics 610 $acomputational fluid dynamics 610 $adeformability 610 $adensity medium 610 $adiabetes 610 $afinite element method 610 $afluorescent chemiluminescence 610 $ahydrophobic dish 610 $ahyperbolic microchannel 610 $aimmersed boundary method 610 $aLattice-Boltzmann method 610 $alens-less 610 $amaster molder using xurography technique 610 $amechanophenotyping 610 $ametastatic potential 610 $amicrofabrication 610 $amicrofluidic chip 610 $amicrofluidic devices 610 $amicrofluidics 610 $amicrostructure 610 $amodified conventional erythrocyte sedimentation rate (ESR) method 610 $amorphological analysis 610 $amultinucleated cells 610 $amultiple microfluidic channels 610 $an/a 610 $anarrow rectangular microchannel 610 $aparticle tracking velocimetry 610 $aPOCT 610 $apolymers 610 $apower-law fluid 610 $apressure-driven flow 610 $aRBC aggregation index 610 $ared blood cell (RBC) aggregation 610 $ared blood cells 610 $ared blood cells (RBCs) 610 $aregression analysis 610 $arheology 610 $aseparation and sorting techniques 610 $asuspension 610 $atwin-image removal 610 $avelocity 610 $aXTC-YF cells 610 $aY-27632 615 7$aTechnology: general issues 700 $aMinas$b Grac?a$4auth$01322341 702 $aCatarino$b Susana$4auth 702 $aLima$b Rui A$4auth 906 $aBOOK 912 $a9910367739803321 996 $aMicro$93034887 997 $aUNINA