LEADER 03446nam 22005775 450 001 9910366621903321 005 20200702152541.0 010 $a3-030-20182-1 024 7 $a10.1007/978-3-030-20182-1 035 $a(CKB)4100000008701651 035 $a(MiAaPQ)EBC5825101 035 $a(DE-He213)978-3-030-20182-1 035 $a(PPN)238489647 035 $a(EXLCZ)994100000008701651 100 $a20190712d2020 u| 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aMulti-scale Extracellular Matrix Mechanics and Mechanobiology /$fedited by Yanhang Zhang 205 $a1st ed. 2020. 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2020. 215 $a1 online resource (401 pages) 225 1 $aStudies in Mechanobiology, Tissue Engineering and Biomaterials,$x1868-2006 ;$v23 311 $a3-030-20181-3 327 $aContributions of extracellular (ECM) constituents to the mechanical function of soft biological tissue -- Structure-based constitutive modeling of ECM mechanics -- Advanced optical imaging of ECM structures in biological systems ?fundamental research and clinical applications -- Discrete fiber network modeling of ECM networks -- Microstructural mechanisms and contributions of elastin and collagen to the elastic and viscoelastic behavior of soft biological tissues -- Scale-dependency of multi-scale ECM mechanics and measurements -- Bridging scales - multi-scale mechanics of engineered and native tissue -- Mechanical and biological interactions between cells and ECM -- Multi-physics modeling of ECM mechanics. 330 $aThis book describes the current state of knowledge in the field of multi-scale ECM mechanics and mechanobiology with a focus on experimental and modelling studies in biomechanical characterization, advanced optical microscopy and imaging, as well as computational modeling. This book also discusses the scale dependency of ECM mechanics, translation of mechanical forces from tissue to cellular level, and advances and challenges in improving our understanding of cellular mechanotransduction in the context of living tissues and organisms. 410 0$aStudies in Mechanobiology, Tissue Engineering and Biomaterials,$x1868-2006 ;$v23 606 $aBiomedical engineering 606 $aBiophysics 606 $aBiological physics 606 $aMechanics 606 $aMechanics, Applied 606 $aBiomedical Engineering and Bioengineering$3https://scigraph.springernature.com/ontologies/product-market-codes/T2700X 606 $aBiological and Medical Physics, Biophysics$3https://scigraph.springernature.com/ontologies/product-market-codes/P27008 606 $aSolid Mechanics$3https://scigraph.springernature.com/ontologies/product-market-codes/T15010 615 0$aBiomedical engineering. 615 0$aBiophysics. 615 0$aBiological physics. 615 0$aMechanics. 615 0$aMechanics, Applied. 615 14$aBiomedical Engineering and Bioengineering. 615 24$aBiological and Medical Physics, Biophysics. 615 24$aSolid Mechanics. 676 $a611.0182 702 $aZhang$b Yanhang$4edt$4http://id.loc.gov/vocabulary/relators/edt 906 $aBOOK 912 $a9910366621903321 996 $aMulti-scale Extracellular Matrix Mechanics and Mechanobiology$92518626 997 $aUNINA