LEADER 05174nam 22006254a 450 001 9910144329103321 005 20170816124433.0 010 $a1-281-31173-1 010 $a9786611311735 010 $a3-527-61248-3 010 $a3-527-61249-1 035 $a(CKB)1000000000376235 035 $a(EBL)481638 035 $a(OCoLC)609855373 035 $a(SSID)ssj0000296865 035 $a(PQKBManifestationID)11253836 035 $a(PQKBTitleCode)TC0000296865 035 $a(PQKBWorkID)10328151 035 $a(PQKB)10578372 035 $a(MiAaPQ)EBC481638 035 $a(EXLCZ)991000000000376235 100 $a20040202d2004 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aFreeze-drying$b[electronic resource] 205 $a2nd, completely rev. and extended ed. /$bGeorg-Wilhelm Oetjen, Peter Haseley. 210 $aWeinheim $cWiley-VCH$dc2004 215 $a1 online resource (409 p.) 300 $aDescription based upon print version of record. 311 $a3-527-30620-X 320 $aIncludes bibliographical references and index. 327 $aFreeze-Drying; Table of Contents; Preface; Preface to the First Edition; 1 Foundations and Process Engineering; 1.1 Freezing; 1.1.1 Amount of Heat, Heat Conductivity, Heat Transfer and Cooling Rate; 1.1.2 Structure of Ice, Solutions and Dispersions; 1.1.3 Influence of Excipients; 1.1.4 Freezing of Cells and Bacteria; 1.1.5 Methods of Structure Analysis; 1.1.5.1 Measurements of Electrical Resistance (ER); 1.1.5.2 Differential Thermal Analysis (DTA); 1.1.5.3 Cryomicroscopy; 1.1.5.4 Differential Scanning Calorimetry (DSC); 1.1.5.5 Nuclear Magnetic Resonance 327 $a1.1.5.6 Thermomechanical Analysis (TMA)1.1.5.7 Dielectric Analysis (DEA); 1.1.5.8 X-ray Diffractometry-Raman Spectroscopy; 1.1.6 Changes of Structure in Freezing or Frozen Products; 1.2 Drying; 1.2.1 Main Drying (Sublimation Drying); 1.2.2 Secondary Drying (Desorption Drying); 1.2.3 Temperature and Pressure Measurement; 1.2.4 Water Vapor Transport During Drying; 1.2.5 Collapse and Recrystallization; 1.2.6 Drying Processes Without Vacuum; 1.3 Storage; 1.3.1 Measurement of the Residual Moisture Content (RM); 1.3.1.1 Gravimetric Method; 1.3.1.2 Karl Fischer (KF) Method 327 $a1.3.1.3 Thermogravimetry (TG, TG/MS)1.3.1.4 Infrared Spectroscopy; 1.3.2 Influence of Vial Stoppers on the Residual Moisture Content; 1.3.3 Qualities of the Dry Substances and Their Changes; 1.4 References for Chapter 1; 2 Installation and Equipment Technique; 2.1 Freezing Installation; 2.1.1 Cooling by Liquids: Shell-freezing and Spin-freezing; 2.1.2 Cooled Surfaces; 2.1.3 Product in the Flow of Cold Air, Foaming and Freezing of Extracts and Pulps; 2.1.4 Droplet Freezing in Cold Liquids; 2.1.5 Freezing by Evaporation of Product Water; 2.2 Components of a Freeze-drying Plant 327 $a2.2.1 Installations for Flasks and Manifolds2.2.2 Drying Chambers and Forms of Trays; Trays for Special Applications; 2.2.3 Shelves and their Cooling and Heating; 2.2.4 Water Vapor Condensers; 2.2.5 Refrigerating Systems and Refrigerants; 2.2.6 Vacuum Pumps; 2.2.7 Inlet Venting Filters; 2.2.8 Vacuum Measuring Systems; 2.2.9 Leak Rate Detection; 2.2.10 Process Control Systems; 2.2.11 Problems, Failures and Deviations; 2.3 Installations up to 10 kg Ice Capacity; 2.3.1 Universal Laboratory Plants; 2.3.2 Pilot Plants; 2.3.3 Manipulators and Stoppering Systems for Vials 327 $a2.3.4 Cleaning Installations, Sterilization by Steam and Vaporized Hydrogen Peroxide (VHP®)2.4 Production Plants; 2.4.1 Loading and Unloading Systems; 2.5 Production Plants for Food; 2.5.1 Discontinuous Plants; 2.5.2 Continuous Plants with Tray Transport; 2.5.3 Continuous Plants with Product Transport by Wipers or by Vibration; 2.6 Process Automation; 2.6.1 Prerequisites for Process and Related Plant Automation; 2.6.2 Control of the Process and Related Plant Data by Thermodynamic Data Measured During the Process: Thermodynamic Lyophilization Control (TLC) 327 $a2.6.2.1 Control of the Process Without Temperature Sensors in the Product 330 $aMany modern pharmaceutical and biological products, e.g. blood derivatives, vaccines, cytostatic drugs, antibiotics, bacteria cultures but also consumer goods such as soluble coffee are freeze-dried to transform perishable substances into a form that can be stored and reconstituted to their almost original state without loss of quality.The book describes the up-to-date fundamentals of freeze-drying, not just presenting the process in all its seven steps theoretically, but explaining it with many practical examples. Many years of experience in freeze-drying allow the authors to supply valua 606 $aFreeze-drying 608 $aElectronic books. 615 0$aFreeze-drying. 676 $a615.19 676 $a660/.28426 700 $aOetjen$b Georg-Wilhelm$0889469 701 $aHaseley$b Peter$0289089 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910144329103321 996 $aFreeze-drying$92139189 997 $aUNINA LEADER 04915nam 22006495 450 001 9910357830703321 005 20251113185458.0 010 $a981-329-804-9 024 7 $a10.1007/978-981-32-9804-0 035 $a(CKB)4100000009758959 035 $a(DE-He213)978-981-32-9804-0 035 $a(MiAaPQ)EBC5973820 035 $a(PPN)258064234 035 $a(MiAaPQ)EBC5973771 035 $a(EXLCZ)994100000009758959 100 $a20191105d2019 u| 0 101 0 $aeng 135 $aurnn|008mamaa 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aAdvances in Sustainable Polymers $eProcessing and Applications /$fedited by Vimal Katiyar, Raghvendra Gupta, Tabli Ghosh 205 $a1st ed. 2019. 210 1$aSingapore :$cSpringer Nature Singapore :$cImprint: Springer,$d2019. 215 $a1 online resource (XXXI, 483 p. 210 illus., 127 illus. in color.) 225 1 $aMaterials Horizons: From Nature to Nanomaterials,$x2524-5392 311 08$a981-329-803-0 327 $aPart I: Sustainable Polymers for Biomedical Applications -- Chapter 1- Biomaterials for Biomedical Devices and Implants -- Chapter 2- Biocompatible Polymer based Nanofibres for Tissue Engineering Application -- Chapter 3- Biodegradable Polymer based Nanohybrids for Controlled Drug Delivery and Implant Applications -- Chapter 4- Biobased Nanohydrogels for Controlled Drug Delivery -- Chapter 5- Resorbable Polymers for Biomedical Applications -- Chapter 6- Carbohydrate Therapeutics Based on Polymer grafted Nanoparticles -- Chapter 6-Hydrogels for Wound Healing Applications Facilitated by Herbal Bioactive Agents -- Chapter 7: Polymeric Nanoparticles for Chemotherapeutic Drug Delivery -- Part II: Sustainable Polymers for Food Packaging Applications -- Chapter 8- Polysaccharide Based Films for Food Packaging and other Application -- Chapter 9- Biopolymer based Polylactic acid for food packaging applications -- Chapter 10- Bacterial Cellulose based Hydrogel Film for Sustainable Food Packaging -- Chapter 11- Biodegradable Polymer Based Blown Films for Food Packaging Application -- Part III: Sustainable Polymers for other emerging application -- Chapter 12- Advances in Biobased Polymer Membranes for CO2 Separation -- Chapter 13- Bio-based Polymers in stimuli responsive membranes -- Chapter 14- Microbial Fuel Cell: A synergistic Flow Approach for Energy Power Generation and Wastewater Treatment -- Chapter 15- Sustainable Polymer based Microfluidic Fuel Cells for Low Power Applications -- Chapter 16- Sustainable Polymeric Nanocomposites for Multifaceted Advanced Applications -- Chapter 17- Bioinspired interfaces for High performance/Advanced application -- Chapter 18- Biobased Polymeric Conductive Materials for Advanced Applications -- Chapter 19- Aerobic Composting of Bioplastics. 330 $aThis book provides a systematic overview of the processing and applications of sustainable polymers. The volume covers recent advances in biomedical, food packaging, fuel cell, membrane, and other emerging applications. The book begins by addressing different sections of biomedical application including use of carbohydrate-based therapeutics, nanohybrids, nanohydrogels, bioresorbable polymers and their composites, polymer-grafted nanobiomaterials for biomedical devices and implants, nanofibres, and others. The second part of this book discusses various processing and packaging materials for food packaging applications. The last section discusses other emerging applications, including using microbial fuel cells for waste water treatment, microfluidic fuel cells for low power applications, among others. This volume will be relevant to researchers working to improve the properties of bio-based materials for their advanced application and wide commercialization. 410 0$aMaterials Horizons: From Nature to Nanomaterials,$x2524-5392 606 $aMaterials$xAnalysis 606 $aPolymers 606 $aMaterials 606 $aGreen chemistry 606 $aCharacterization and Analytical Technique 606 $aPolymers 606 $aMaterials Engineering 606 $aGreen Chemistry 615 0$aMaterials$xAnalysis. 615 0$aPolymers. 615 0$aMaterials. 615 0$aGreen chemistry. 615 14$aCharacterization and Analytical Technique. 615 24$aPolymers. 615 24$aMaterials Engineering. 615 24$aGreen Chemistry. 676 $a620.11 702 $aKatiyar$b Vimal$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aGupta$b Raghvendra$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aGhosh$b Tabli$4edt$4http://id.loc.gov/vocabulary/relators/edt 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910357830703321 996 $aAdvances in Sustainable Polymers$91732467 997 $aUNINA