LEADER 04569nam 22006495 450 001 9910357821003321 005 20240306155232.0 010 $a3-030-28733-5 024 7 $a10.1007/978-3-030-28733-7 035 $a(CKB)4100000009939791 035 $a(MiAaPQ)EBC5984527 035 $a(DE-He213)978-3-030-28733-7 035 $a(PPN)242849555 035 $a(EXLCZ)994100000009939791 100 $a20191123d2019 u| 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 14$aThe Art of Writing Reasonable Organic Reaction Mechanisms /$fby Robert B. Grossman 205 $a3rd ed. 2019. 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2019. 215 $a1 online resource (447 pages) $cillustrations 300 $aIncludes index. 311 $a3-030-28732-7 327 $aThe Basics -- Polar Reactions under Basic Conditions -- Polar Reactions under Acidic Conditions -- Pericyclic Reactions -- Free-Radical Reactions.-Transition-Metal-Mediated and -Catalyzed Reactions -- Mixed-Mechanism Problems. 330 $aIntended for students of intermediate organic chemistry, this text shows how to write a reasonable mechanism for an organic chemical transformation. The discussion is organized by types of mechanisms and the conditions under which the reaction is executed, rather than by the overall reaction as is the case in most textbooks. The treatment emphasizes unifying principles, showing how common mechanisms link seemingly disparate reactions. Each chapter discusses common mechanistic pathways and suggests practical tips for drawing them. Worked problems are included in the discussion of each mechanism, and ?common error alerts? are scattered throughout the text to warn readers about pitfalls and misconceptions that bedevil students. Each chapter is capped by a large problem set. The author has drawn on his own research and the current literature to ensure that appropriate attention is given to topics across the range of modern organic chemistry. The text is unique in its inclusion of a chapter on reactions mediated or catalyzed by transition metals, an area in which mechanistic understanding is now essential. More modern topics such as olefin metathesis and cycloaromatization are covered without giving short shrift to more traditional areas such as carbonyl chemistry. The text assumes a basic knowledge of organic chemistry. It can be used either in a formal course or by students working on their own, and will be particularly useful for graduate students studying for qualifying examinations. It will also be useful to students and researchers in biochemistry, pharmacology, and inorganic chemistry. The third edition includes greater discussion of the reactions of biological cofactors such as thiamine and pyridoxal, and discussions of modern developments such as metal-catalyzed C?H activation reactions have been added. In terms of stylistic improvements, the author has introduced color into drawings to improve visual clarity and has improved the depictions of radical anions and radical chain reactions. . 606 $aChemistry, Organic 606 $aBiochemistry 606 $aPharmacology 606 $aChemistry, Inorganic 606 $aPolymers 606 $aOrganic Chemistry$3https://scigraph.springernature.com/ontologies/product-market-codes/C19007 606 $aBiochemistry, general$3https://scigraph.springernature.com/ontologies/product-market-codes/L14005 606 $aPharmacology/Toxicology$3https://scigraph.springernature.com/ontologies/product-market-codes/B21007 606 $aInorganic Chemistry$3https://scigraph.springernature.com/ontologies/product-market-codes/C16008 606 $aPolymer Sciences$3https://scigraph.springernature.com/ontologies/product-market-codes/C22008 615 0$aChemistry, Organic. 615 0$aBiochemistry. 615 0$aPharmacology. 615 0$aChemistry, Inorganic. 615 0$aPolymers. 615 14$aOrganic Chemistry. 615 24$aBiochemistry, general. 615 24$aPharmacology/Toxicology. 615 24$aInorganic Chemistry. 615 24$aPolymer Sciences. 676 $a547.139 700 $aGrossman$b Robert B$4aut$4http://id.loc.gov/vocabulary/relators/aut$0150761 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910357821003321 996 $aArt of writing reasonable organic reaction mechanisms$977830 997 $aUNINA