LEADER 04744nam 22006735 450 001 9910350355803321 005 20200630122525.0 010 $a981-13-3585-0 024 7 $a10.1007/978-981-13-3585-3 035 $a(CKB)4100000009158708 035 $a(MiAaPQ)EBC5844355 035 $a(DE-He213)978-981-13-3585-3 035 $a(PPN)238486680 035 $a(EXLCZ)994100000009158708 100 $a20190730d2019 u| 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aModels, Molecules and Mechanisms in Biogerontology $ePhysiological Abnormalities, Diseases and Interventions /$fedited by Pramod C. Rath 205 $a1st ed. 2019. 210 1$aSingapore :$cSpringer Singapore :$cImprint: Springer,$d2019. 215 $a1 online resource (434 pages) 311 $a981-13-3584-2 327 $aPart I Alterations in Nervous System, Genes, Hormones and Immunity during Aging. - Neurological problems of the Elderly -- Molecular marker and therapeutic regimen for neurodegenerative diseases -- Neurodegeneration during Aging: Role of Oxidative Stress through Epigenetic Modifications -- Polyglucosan Bodies in Aged Brain and Neurodegeneration: Cause or Consequence? -- Signaling of Nociceptors and Pain Perception: Impact of age -- Association between Ageing and REM sleep loss: Noradrenaline acting as a mediator -- Age related changes in the human retina: a role for oxidative stress. - Ageing: Influence on Duchenne muscular dystrophy (DMD) and Becker muscular dystrophy (BMD) -- Mitophagy, Diseases and Aging -- Genetics, Ageing and Human Health -- Genetic Syndromes and Aging -- Role of Stress and Hormones of the Hypothalamic-Pituitary-Adrenal (HPA) Axis in Aging -- Sex Steroids, Cognate Receptors and Aging -- Immunosenesence, Inflammaging and their implications for Cancer and Anemia -- Bone Marrow Stem Cells, Aging and Age-related Diseases -- Part II Interventions for Healthy Aging -- Infantile radiation and Aging Stresses: Effects of Calorie and Dietary Restrictions -- Mechanisms and Late Life Intervention of Aging -- Healthy Ageing and Cancer in Humans -- Nutrition for elderly -- Care of older persons in India: scope of policy and technology tools. 330 $aThis book examines the basic cellular and molecular mechanisms associated with aging. It comprehensively describes the genetic, epigenetic, biochemical and metabolic regulation of aging, as well as some important age-related diseases. Divided into two major sections, it takes readers through the various aspects of aging in a story-like manner and suggests various interventions for healthy aging, such as dietary restriction, regular exercise, nutrition and maintaining a balanced and a non-stressful lifestyle. It describes the implications of aging on the nervous system, metabolism, immunity and stem cells as well as care for the elderly. The book is an ideal companion for both new and established researchers in the field and is also useful for educators, clinicians and policy makers. 606 $aBiomedical engineering 606 $aGeriatrics 606 $aMolecular biology 606 $aHuman genetics 606 $aMetabolism 606 $aRegenerative medicine 606 $aTissue engineering 606 $aBiomedical Engineering/Biotechnology$3https://scigraph.springernature.com/ontologies/product-market-codes/B24000 606 $aGeriatrics/Gerontology$3https://scigraph.springernature.com/ontologies/product-market-codes/H33150 606 $aMolecular Medicine$3https://scigraph.springernature.com/ontologies/product-market-codes/B1700X 606 $aHuman Genetics$3https://scigraph.springernature.com/ontologies/product-market-codes/B12008 606 $aMetabolomics$3https://scigraph.springernature.com/ontologies/product-market-codes/L15030 606 $aRegenerative Medicine/Tissue Engineering$3https://scigraph.springernature.com/ontologies/product-market-codes/L16080 615 0$aBiomedical engineering. 615 0$aGeriatrics. 615 0$aMolecular biology. 615 0$aHuman genetics. 615 0$aMetabolism. 615 0$aRegenerative medicine. 615 0$aTissue engineering. 615 14$aBiomedical Engineering/Biotechnology. 615 24$aGeriatrics/Gerontology. 615 24$aMolecular Medicine. 615 24$aHuman Genetics. 615 24$aMetabolomics. 615 24$aRegenerative Medicine/Tissue Engineering. 676 $a612.67 702 $aRath$b Pramod C$4edt$4http://id.loc.gov/vocabulary/relators/edt 906 $aBOOK 912 $a9910350355803321 996 $aModels, Molecules and Mechanisms in Biogerontology$91965994 997 $aUNINA