LEADER 03170nam 22005175 450 001 9910350349503321 005 20230928154240.0 010 $a981-13-9077-0 024 7 $a10.1007/978-981-13-9077-7 035 $a(CKB)4100000009757375 035 $a(MiAaPQ)EBC5916288 035 $a(DE-He213)978-981-13-9077-7 035 $a(PPN)260303194 035 $a(EXLCZ)994100000009757375 100 $a20190930d2019 u| 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aAdvances in Membrane Proteins $eBuilding, Signaling and Malfunction /$fedited by Yu Cao 205 $a1st ed. 2019. 210 1$aSingapore :$cSpringer Singapore :$cImprint: Springer,$d2019. 215 $a1 online resource (132 pages) 311 $a981-13-9076-2 327 $a1. Cell adhesion molecules and development -- 2. Receptors and signal transduction -- 3. Single-transmembrane proteins and antibody drugs -- 4. Viral membrane proteins -- 5. Biosynthesis and folding of oily peptide chains -- 6. Quality control in producing membrane proteins. 330 $aThis book reviews recent advances regarding the biochemical and biophysical properties of membrane proteins and their applications in biomedicine. Divided into two thematic parts, this second volume addresses proteins? formation, signaling and malfunctions. It covers a number of important membrane proteins including receptors, cell adhesion molecules, single-transmembrane proteins and viral membrane proteins, and discusses their structures, functions, related diseases, and roles in drug discovery in detail. In turn, the book elucidates the lifecycle of membrane proteins, including their synthesis and facilitated folding process, as well as QC procedures for their production. Additional topics include fundamental concepts, the latest findings, and critical puzzles yet to be solved. Given its scope, the book will appeal to a broad readership in the field of membrane structural and functional biology. Junior scientists can use it as an introduction to the field, while advanced scientists will find a broader view of the field beyond their area of specialization. . 606 $aProteins  606 $aPharmaceutical technology 606 $aProtein Science$3https://scigraph.springernature.com/ontologies/product-market-codes/L14040 606 $aPharmaceutical Sciences/Technology$3https://scigraph.springernature.com/ontologies/product-market-codes/B21010 606 $aProtein Structure$3https://scigraph.springernature.com/ontologies/product-market-codes/L14050 615 0$aProteins . 615 0$aPharmaceutical technology. 615 14$aProtein Science. 615 24$aPharmaceutical Sciences/Technology. 615 24$aProtein Structure. 676 $aQP552.M44 702 $aCao$b Yu$c(Of Shanghai Jiao Tong University School of Medicine),$4edt$4http://id.loc.gov/vocabulary/relators/edt 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910350349503321 996 $aAdvances in Membrane Proteins$91994015 997 $aUNINA