LEADER 03831nam 22006015 450 001 9910350349103321 005 20200630120356.0 010 $a981-13-9367-2 024 7 $a10.1007/978-981-13-9367-9 035 $a(CKB)4100000009757387 035 $a(MiAaPQ)EBC5963197 035 $a(DE-He213)978-981-13-9367-9 035 $a(PPN)248602047 035 $a(EXLCZ)994100000009757387 100 $a20191018d2019 u| 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aStructural Immunology /$fedited by Tengchuan Jin, Qian Yin 205 $a1st ed. 2019. 210 1$aSingapore :$cSpringer Singapore :$cImprint: Springer,$d2019. 215 $a1 online resource (xiii, 226 pages) $cillustrations 225 1 $aAdvances in Experimental Medicine and Biology,$x0065-2598 ;$v1172 311 $a981-13-9366-4 327 $aStructural basis for signalling through shared common g chain cytokines -- MHC Molecules, T Cell Receptors, Natural Killer Cell Receptors, and Viral Immunoevasins?Key Elements of Adaptive and Innate Immunity -- Structures of Immune Checkpoints: An Overview on the CD28-B7 Family -- Interleukin-10 family cytokines immunobiology and structure -- Structural insights into the interleukin-17 family cytokines and their receptors -- Structural biology of NOD-like receptors -- AIM2 Inflammasome Assembly and Signaling -- Structures of RIG-I-like receptors and insights into viral RNA sensing -- Structural Insight of Gasdermin Family Driving Pyroptotic Cell Death -- NF-?B, I?B, and IKK: Integral Components of Immune System Signaling. 330 $aThis book presents a comprehensive overview of important immune molecules and their structure-function relationships. The immune system is highly complex, consisting of a network of molecules, cells, tissues and organs, and the immune reaction is involved in various physiological as well as pathological processes, including development, self-tolerance, infection, immunity, and cancer. Numerous molecules participate in immune recognition, inhibition and activation, and these important immune molecules can be roughly divided into cell surface receptors, intracellular receptors and intracellular signaling molecules. The study of how these immune molecules function at molecular level has laid the foundation for understanding the immune system. The book provides researchers and students with the latest research advances concerning the structural biology of key immune molecules/pathways, and offers immunologists essential insights into how these immune molecules function. 410 0$aAdvances in Experimental Medicine and Biology,$x0065-2598 ;$v1172 606 $aImmunology 606 $aProteins  606 $aMolecular biology 606 $aImmunology$3https://scigraph.springernature.com/ontologies/product-market-codes/B14000 606 $aProtein Structure$3https://scigraph.springernature.com/ontologies/product-market-codes/L14050 606 $aMolecular Medicine$3https://scigraph.springernature.com/ontologies/product-market-codes/B1700X 606 $aReceptors$3https://scigraph.springernature.com/ontologies/product-market-codes/L14110 615 0$aImmunology. 615 0$aProteins . 615 0$aMolecular biology. 615 14$aImmunology. 615 24$aProtein Structure. 615 24$aMolecular Medicine. 615 24$aReceptors. 676 $a616.079 702 $aJin$b Tengchuan$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aYin$b Qian$4edt$4http://id.loc.gov/vocabulary/relators/edt 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910350349103321 996 $aStructural Immunology$91994013 997 $aUNINA