LEADER 01149nam2-2200409---450- 001 990001749340203316 005 20040611163237.0 035 $a000174934 035 $aUSA01000174934 035 $a(ALEPH)000174934USA01 035 $a000174934 100 $a20040611d196878--km-y0itay0103----ba 101 0 $aita 102 $aUS 105 $aa|||||||001yy 200 1 $a<<10.>> : Come guardare l'arte$fa cura di Bernard Myers 210 $aNew York [etc.]$cGrolier$d1968 215 $a255 p.$cill.$d25 cm 410 0$12001 454 1$12001 461 1$1001000138122$12001$a<> libro d'arte 606 0 $aArte Storia$xStoria$zMedioevo 606 0 $aArte paleocristiana 606 0 $aArte romana 606 0 $aArte romanica 606 0 $aArte gotica 702 1$aMYERS,$bBernard S. 801 0$aIT$bsalbc$gISBD 912 $a990001749340203316 951 $a703 LIB$b47545 L.M.$c703 959 $aBK 969 $aUMA 979 $aSIAVER$b90$c20040611$lUSA01$h1623 979 $aSIAVER$b90$c20040611$lUSA01$h1626 979 $aSIAVER$b90$c20040611$lUSA01$h1632 996 $aCome guardare l'arte$9946175 997 $aUNISA LEADER 03628nam 22005175 450 001 9910350312903321 005 20181112071520.0 010 $a981-13-2402-6 024 7 $a10.1007/978-981-13-2402-4 035 $a(CKB)4100000006671787 035 $a(MiAaPQ)EBC5517004 035 $a(DE-He213)978-981-13-2402-4 035 $a(EXLCZ)994100000006671787 100 $a20180914d2019 u| 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aPatient-Specific Controller for an Implantable Artificial Pancreas$b[electronic resource] /$fby Yvonne Ho 205 $a1st ed. 2019. 210 1$aSingapore :$cSpringer Singapore :$cImprint: Springer,$d2019. 215 $a1 online resource (97 pages) 225 1 $aSpringer Theses, Recognizing Outstanding Ph.D. Research,$x2190-5053 311 $a981-13-2401-8 327 $aIntroduction -- Glucose Metabolism and Diabetes -- Literature Review -- Design of an Implantable Artificial Pancreas -- Model Predictive Controller using Interior Point and Ant Algorithm -- In Vivo Experiment of the Implantable Artificial Pancreas -- Parameter Estimation for Nonlinear Mathematical Model -- Conclusion and Future Work. 330 $aThe thesis focuses on the control of blood glucose devices and design of implantable devices, and offers valuable insights on diabetes mellitus and related physiology and treatments. Diabetes mellitus is a widespread chronic disease in the modern world that affects millions of people around the globe. In Singapore, one in ten of the population has diabetes, and the severity of the problem has prompted the country?s prime minister to talk about the disease at the National Day Rally in 2017. Designing an artificial pancreas that can provide effective blood glucose control for individuals with diabetes is one of the most challenging engineering problems. The author reports on research into the development of an implantable artificial pancreas that can regulate blood glucose levels by delivering appropriate dosages of insulin when necessary. By sensing blood glucose and injecting insulin directly into the vein, the implantable device aims to remove delays that occur with subcutaneous blood glucose sensing and insulin delivery. Preliminary in-vitro and in-vivo experimental results suggest that the implantable device for blood glucose control could be a clinically viable alternative to pancreas transplant. 410 0$aSpringer Theses, Recognizing Outstanding Ph.D. Research,$x2190-5053 606 $aBiomedical engineering 606 $aDiabetes 606 $aBiomedical Engineering and Bioengineering$3http://scigraph.springernature.com/things/product-market-codes/T2700X 606 $aBiomedical Engineering/Biotechnology$3http://scigraph.springernature.com/things/product-market-codes/B24000 606 $aDiabetes$3http://scigraph.springernature.com/things/product-market-codes/H33045 606 $aControl and Systems Theory$3http://scigraph.springernature.com/things/product-market-codes/T19010 615 0$aBiomedical engineering. 615 0$aDiabetes. 615 14$aBiomedical Engineering and Bioengineering. 615 24$aBiomedical Engineering/Biotechnology. 615 24$aDiabetes. 615 24$aControl and Systems Theory. 676 $a616.462025 700 $aHo$b Yvonne $4aut$4http://id.loc.gov/vocabulary/relators/aut$0871313 906 $aBOOK 912 $a9910350312903321 996 $aPatient-Specific Controller for an Implantable Artificial Pancreas$91945079 997 $aUNINA