LEADER 03466nam 22005055 450 001 9910350309403321 005 20181119213838.0 010 $a981-13-1474-8 024 7 $a10.1007/978-981-13-1474-2 035 $a(CKB)4100000007158817 035 $a(MiAaPQ)EBC5601928 035 $a(DE-He213)978-981-13-1474-2 035 $a(EXLCZ)994100000007158817 100 $a20181119d2019 u| 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aArticular Cartilage Dynamics$b[electronic resource] /$fby David W. Smith, Bruce S. Gardiner, Lihai Zhang, Alan J. Grodzinsky 205 $a1st ed. 2019. 210 1$aSingapore :$cSpringer Singapore :$cImprint: Springer,$d2019. 215 $a1 online resource (lxiii, 738 pages) 311 $a981-13-1473-X 327 $aIntroduction to Articular Cartilage -- Cartilage tissue homeostasis -- Cartilage tissue dynamics -- Lubrication, Friction and Wear in Diarthroidal Joints -- A systems approach to articular cartilage -- Theory for modeling articular cartilage -- Computational modeling of articular cartilage. 330 $aThis book explains the anatomy and physiology of cartilage tissue in an integrated way. The emphasis is on how cartilage tissue functions and maintains homeostasis in a challenging mechanical environment. Supported by hundreds of references, the book posts new hypotheses explaining how cartilage adapts and achieves homeostasis in vivo, and tests them against available data. This exploratory approach creates a sense of discovery that the reader can join, or perhaps test themselves through their own research. The main benefit will be obtained by research students and professors looking to understand the deeper concepts that will further their own research, or clinicians (including health professionals and surgeons) who want to gain a deeper physiological understanding of cartilage tissue, which can then serve as a basis for more rational clinical decision-making they need to make on a daily basis. To help bridge the gap between basic science and clinically relevant joint disease, applications and interpretations of key physiological concepts are discussed in the context of osteoarthritis at the end of most chapters. 606 $aBiomedical engineering 606 $aMedical physics 606 $aBiomedical Engineering and Bioengineering$3http://scigraph.springernature.com/things/product-market-codes/T2700X 606 $aMedical and Radiation Physics$3http://scigraph.springernature.com/things/product-market-codes/P27060 606 $aRegenerative Medicine/Tissue Engineering$3http://scigraph.springernature.com/things/product-market-codes/L16080 615 0$aBiomedical engineering. 615 0$aMedical physics. 615 14$aBiomedical Engineering and Bioengineering. 615 24$aMedical and Radiation Physics. 615 24$aRegenerative Medicine/Tissue Engineering. 676 $a611.0183 700 $aSmith$b David W$4aut$4http://id.loc.gov/vocabulary/relators/aut$0148124 702 $aGardiner$b Bruce S$4aut$4http://id.loc.gov/vocabulary/relators/aut 702 $aZhang$b Lihai$4aut$4http://id.loc.gov/vocabulary/relators/aut 702 $aGrodzinsky$b Alan J$4aut$4http://id.loc.gov/vocabulary/relators/aut 906 $aBOOK 912 $a9910350309403321 996 $aArticular Cartilage Dynamics$92035900 997 $aUNINA