LEADER 03468nam 2200445 450 001 9910350233303321 005 20190209194800.0 010 $a981-13-3630-X 024 7 $a10.1007/978-981-13-3630-0 035 $a(CKB)4100000007610961 035 $a(DE-He213)978-981-13-3630-0 035 $a(MiAaPQ)EBC5693500 035 $a(EXLCZ)994100000007610961 100 $a20190301d2019 uy 0 101 0 $aeng 135 $aurnn|008mamaa 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aCadmium toxicity $enew aspects in human disease, rice contamination, and cytotoxicity /$fSeiichiro Himeno, Keiko Aoshima, editors 210 1$aGateway East, Singapore :$cSpringer,$d2019. 215 $a1 online resource (VIII, 190 p. 68 illus., 51 illus. in color.) 225 1 $aCurrent Topics in Environmental Health and Preventive Medicine,$x2364-8333 311 $a981-13-3629-6 327 $aOverview. Overview of historical and current problems of cadmium pollution in Japan -- Health effects of cadmium in human populations and its relation to cadmium exposure levels. History and present status of Itai-Itai disease -- Pathophysiology of renal and bone lesions in Itai-itai disease -- A long-term follow-up study of the residents exposed to cadmium in Kakehashi River basin -- Effects of cadmium exposure on life prognosis -- Evaluation of cadmium exposure and health effects among rice farmers in Akita prefecture -- Cadmium intake from foods among general population in Japan and Asia -- Rice contamination by cadmium and its remediation. Regulation of cadmium contents in rice -- Molecular mechanism of cadmium accumulation in rice -- Mitigation technologies of cadmium and arsenic in rice -- Development of low-cadmium-accumulating rice -- New aspects in the mechanisms of cadmium toxicity. Novel mechanisms of cadmium-induced cell death -- Cadmium transport and toxicity in the kidney -- Disturbance in phosphorus metabolism by cadmium exposure. 330 $aThis volume focuses on cadmium (Cd) exposure, its effects on human health, the mechanism of Cd accumulation and the development of mitigation technologies. Further, it discusses clinical, epidemiological, agricultural, toxicological, and biochemical aspects of Cd pollution and presents recent biochemical studies on molecular mechanisms of Cd cytotoxicity and cellular transport as well as the mechanism of Cd-induced disturbances in phosphorus (P) metabolism. It also provides insights into the pathophysiology of itai-itai disease, a serious condition caused by Cd pollution. Cadmium -New Aspects in Human Disease, Rice Contamination, and Cytotoxicity- is a valuable resource for scientists involved in heavy metal toxicology, botanical sciences, and regulatory sciences. Addressing the features of Cd pollution in the past and in the present, as well as future perspectives, this is a must-have book for students, researchers and practitioners interested in global and local metal pollution. 410 0$aCurrent Topics in Environmental Health and Preventive Medicine,$x2364-8333 606 $aCadmium$xToxicology 615 0$aCadmium$xToxicology. 676 $a613 676 $a614.44 702 $aHimeno$b Seiichiro 702 $aAoshima$b Keiko 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910350233303321 996 $aCadmium Toxicity$91736105 997 $aUNINA