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010   $a981-13-1465-9
024 7 $a10.1007/978-981-13-1465-0
035   $a(CKB)4100000008876575
035   $a(DE-He213)978-981-13-1465-0
035   $a(MiAaPQ)EBC5788936
035   $a(PPN)262174960
035   $a(EXLCZ)994100000008876575
100   $a20190611d2019      u|         0
101 0 $aeng
135   $aurnn|008mamaa
181   $ctxt$2rdacontent
182   $cc$2rdamedia
183   $acr$2rdacarrier
200 10$aAlcoholic/Non-Alcoholic Digestive Diseases /$fedited by Hitoshi Yoshiji, Kosuke Kaji
205   $a1st ed. 2019.
210  1$aSingapore :$cSpringer Singapore :$cImprint: Springer,$d2019.
215   $a1 online resource (VIII, 166 p. 25 illus., 19 illus. in color.) 
311   $a981-13-1464-0 
327   $aPart 1 Alcoholic/Nonalcoholic Gastrointestinal Diseases.-1 Alcohol-induced DNA injury in esophagus cancer.-2 Metabolic diseases and GERD -- 3 Post H. pylori gastric diseases.-4 New perspectives in gastric cancer.-5 Role of alcohol and metabolic diseases in colon cancer -- Part 2 Alcoholic/Nonalcoholic Liver Diseases -- 6 Alcoholic liver injury -- 7 Diabetes in liver diseases -- 8 Obesity and hepatocarcinogenesis -- 9 Microbiota in alcoholic liver disease.-10 Microbiota in non-alcoholic liver disease -- 11 Role of oxidative stress in liver disease -- 12 Role of apoptosis in liver disease -- Part 3 Alcoholic/Nonalcoholic Pancreatic Diseases -- 13 Genetic factor in pancreas diseases -- 14 New perspectives in pancreas cancer.
330   $aThis book describes the latest advances concerning the molecular mechanisms of and therapeutic strategies for alcohol- and non-alcohol-related digestive diseases. Alcohol abuse causes not only liver injury but can harm various organs, resulting in esophageal and colorectal cancers, GERD, pancreatitis, etc. Similar to alcoholic abuse, metabolic syndrome based on obesity and diabetes is also strongly associated with the development of various digestive diseases. Although these diseases may be differentiated by the presence or absence of alcohol intake, the pathologic findings and pathogenesis reveal a number of similarities. This volume covers clinical and basic approaches for esophageal, gastric, hepatic, colorectal and pancreatic diseases associated with alcohol abuse and metabolic syndrome; further, it discusses the roles of microbiota, oxidative stress, and apoptosis, the critical factors causing alcoholic and metabolic digestive diseases. Also, it showcases new pathological and therapeutic perspectives in gastric and pancreatic cancers. Alcoholic/Non-Alcoholic Digestive Diseases will provide invaluable information for doctors specializing in gastroenterology and hepatology and researchers seeking new research on digestive diseases based on alcohol consumption and obesity.
606   $aGastroenterology
606   $aHepatology
606   $aMetabolism$xDisorders
606   $aGastroenterology$3https://scigraph.springernature.com/ontologies/product-market-codes/H33061
606   $aHepatology$3https://scigraph.springernature.com/ontologies/product-market-codes/H33088
606   $aMetabolic Diseases$3https://scigraph.springernature.com/ontologies/product-market-codes/H33118
615  0$aGastroenterology.
615  0$aHepatology.
615  0$aMetabolism$xDisorders.
615 14$aGastroenterology.
615 24$aHepatology.
615 24$aMetabolic Diseases.
676   $a616.33
702   $aYoshiji$b Hitoshi$4edt$4http://id.loc.gov/vocabulary/relators/edt
702   $aKaji$b Kosuke$4edt$4http://id.loc.gov/vocabulary/relators/edt
906   $aBOOK
912   $a9910350228403321
996   $aAlcoholic$91734923
997   $aUNINA