LEADER 03463nam 22005775 450 001 9910349560103321 005 20200707033356.0 010 $a3-030-20245-3 024 7 $a10.1007/978-3-030-20245-3 035 $a(CKB)4100000008742960 035 $a(MiAaPQ)EBC5837796 035 $a(DE-He213)978-3-030-20245-3 035 $a(PPN)238491927 035 $a(EXLCZ)994100000008742960 100 $a20190723d2019 u| 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aAtherosclerosis Pathogenesis and Microvascular Dysfunction /$fby Axel Haverich, Erin Colleen Boyle 205 $a1st ed. 2019. 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2019. 215 $a1 online resource (135 pages) 311 $a3-030-20244-5 327 $aIntroduction -- Atherosclerosis Risk Factors -- The Effect Of Growth And Aging On Vascular Architecture -- Incriminating Evidence For The Role Of The Microvasculature In Atherosclerosis -- Risk Factors And Prevention In Light Of Atherosclerosis Being A Microvascular Disease -- New Ways To Target Vasa Vasorum For The Prevention And Treatment Of Atherosclerosis -- Outstanding Questions and Future Directions. . 330 $aThis book provides new perspectives on the pathogenesis of atherosclerosis. Chapters cover atherosclerosis risk factors, the effect of growth and aging on vascular architecture, and the crucial role the microvasculature plays in atherosclerosis development. Microvascular dysfunction would explain why the well-known risk factors actually put individuals at higher risk. This pathomechanism would also hold true not only for obstructive atheroma formation but also for aneurysmal dilatation as well as for aortic and peripheral artery dissection. When seen through this lens, novel preventive and therapeutic opportunities can be envisioned. Atherosclerosis Pathogenesis and Microvascular Dysfunction proposes a single unifying mechanism of atherosclerosis development and describes potential preventative and therapeutic avenues based on this concept. It therefore represents a timely and valuable resource for internal medicine, cardiology, angiology cardiovascular surgeons, pathology clinicians, researchers, trainees, and students. 606 $aCardiology 606 $aCardiac surgery 606 $aAngiology 606 $aPathology 606 $aCardiology$3https://scigraph.springernature.com/ontologies/product-market-codes/H33037 606 $aCardiac Surgery$3https://scigraph.springernature.com/ontologies/product-market-codes/H59028 606 $aAngiology$3https://scigraph.springernature.com/ontologies/product-market-codes/H33010 606 $aPathology$3https://scigraph.springernature.com/ontologies/product-market-codes/H4800X 615 0$aCardiology. 615 0$aCardiac surgery. 615 0$aAngiology. 615 0$aPathology. 615 14$aCardiology. 615 24$aCardiac Surgery. 615 24$aAngiology. 615 24$aPathology. 676 $a616.136 676 $a616.136 700 $aHaverich$b Axel$4aut$4http://id.loc.gov/vocabulary/relators/aut$01064802 702 $aBoyle$b Erin Colleen$4aut$4http://id.loc.gov/vocabulary/relators/aut 906 $aBOOK 912 $a9910349560103321 996 $aAtherosclerosis Pathogenesis and Microvascular Dysfunction$92541027 997 $aUNINA