LEADER 03491nam 22004815 450 001 9910349556803321 005 20200702115406.0 010 $a3-030-22258-6 024 7 $a10.1007/978-3-030-22258-1 035 $a(CKB)4100000008869923 035 $a(MiAaPQ)EBC5844344 035 $a(DE-He213)978-3-030-22258-1 035 $a(PPN)238492109 035 $a(EXLCZ)994100000008869923 100 $a20190730d2019 u| 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aIntrahepatic Cholangiocarcinoma $eDiagnosis and Management /$fedited by Timothy M. Pawlik, Jordan M. Cloyd, Mary Dillhoff 205 $a1st ed. 2019. 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2019. 215 $a1 online resource (221 pages) 311 $a3-030-22257-8 327 $aEpidemiology and Risk Factors -- Clinical Presentation and Diagnosis -- Staging and Prognosis -- Imaging -- Surgical Treatment -- Management of the Nodal Basin -- Pathologic Assessment -- Systemic Therapy -- Percutaneous Ablation -- Transarterial Therapies -- Radiotherapy -- Molecular Pathogenesis: From Inflammation And Cholestasis To A Microenvironment-Driven Tumor -- Clinical Trials and Novel/Emerging Treatment. 330 $aThis book provides a comprehensive review of the epidemiology, molecular pathogenesis, diagnosis and treatment of intrahepatic cholangiocarcinoma (ICC). It brings together an impressive group of international experts in cholangiocarcinoma research and clinical care. The book was organized and written to aid the clinician?s understanding of emerging research in cholangiocarcinoma and its application to the clinical care of patients with ICC. Each chapter details the scientific evidence to support clinical decisions that are needed to care for these complex patients. Focused chapters detail the epidemiology, diagnostic evaluation, as well as staging and prognosis of this disease. In addition to dedicated chapters on surgical management of ICC, a broad emphasis on locoregional therapies, including percutaneous ablation and transarterial therapies, is included. An up-to-date overview of the molecular pathogenesis and pathological assessment of ICC is detailed prior to chapters focusing on systemic chemotherapy and emerging novel therapy options. Intrahepatic Cholangiocarcinoma is not only an invaluable resource for many as they seek to provide the best multidisciplinary cancer care to patients with ICC, but also an opportunity to identify new avenues of scientific discovery that lead to significant advances in the diagnosis and management of ICC. 606 $aSurgery 606 $aSurgical oncology 606 $aGeneral Surgery$3https://scigraph.springernature.com/ontologies/product-market-codes/H59044 606 $aSurgical Oncology$3https://scigraph.springernature.com/ontologies/product-market-codes/H59150 615 0$aSurgery. 615 0$aSurgical oncology. 615 14$aGeneral Surgery. 615 24$aSurgical Oncology. 676 $a616.99436 702 $aPawlik$b Timothy M$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aCloyd$b Jordan M$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aDillhoff$b Mary$4edt$4http://id.loc.gov/vocabulary/relators/edt 906 $aBOOK 912 $a9910349556803321 996 $aIntrahepatic Cholangiocarcinoma$91736789 997 $aUNINA