LEADER 04752nam 22006735 450 001 9910349465703321 005 20200703124740.0 010 $a981-13-1453-5 010 $a981-13-1452-7 024 7 $a10.1007/978-981-13-1453-7 035 $a(CKB)4100000008525666 035 $a(MiAaPQ)EBC5776150 035 $a(DE-He213)978-981-13-1453-7 035 $a(PPN)236520431 035 $a(EXLCZ)994100000008525666 100 $a20190513d2019 u| 0 101 0 $aeng 135 $aurnn|008mamaa 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aAdvancement in the Pathophysiology of Cerebral Stroke /$fedited by Ranjana Patnaik, Amit Kumar Tripathi, Ashish Dwivedi 205 $a1st ed. 2019. 210 1$aSingapore :$cSpringer Singapore :$cImprint: Springer,$d2019. 215 $a1 online resource (VIII, 189 p. 23 illus., 12 illus. in color.) 327 $aChapter 1. Cerebral stroke: An Introduction -- Chapter 2. Inflammation, oxidative stress, and neurodegeneration -- Chapter 3. Stroke induced blood brain barrier damage -- Chapter 4. Regulation of calcium ions in ischemic neuronal cell -- Chapter 5. Ischemic stroke induced endoplasmic reticulum stress -- Chapter 6. The role of autophagy in ischemic stroke: friend or foe?- Chapter 7. Critical role of mitochondrial autophagy in cerebral stroke -- Chapter 8. Application of neuroimaging in the identification of the pinpoint location of blockage -- Chapter 9. Emerging role of the electromagnetic field in stroke -- Chapter 10. Stem?cell therapies for stroke -- Chapter 11. MicroRNA: Significance to?stroke?diagnosis, prognosis, and therapy -- Chapter 12. Therapeutic Aspects of Nanomedicines in Stroke Treatment -- Chapter 13. Neuroprotective potential of small molecule phytochemicals against stroke -- Chapter 14. Role of UV irradiation on neuroprotective potential of phytochemicals -- Chapter 15. Post-stroke treatment strategies, management, and rehabilitation. 330 $aThis book provides detailed and comprehensive mechanistic insights of the various risk factors that lead to the ischemic stroke and the novel therapeutic interventions against it. The first section discusses the different ischemic cerebral stroke-induced inflammatory pathways and dysfunctionality of blood-brain barrier. The later sections of the book deals with the role of endoplasmic reticulum stress and mitophagy in cerebral stroke and introduces the different neuroimaging techniques such as Computed tomography (CT), Magnetic resonance imaging (MRI), Positron emission tomography (PET) and Single-Photon emission computed tomography (SPECT) that are used to identify the arterial blockages. The final section comprises of chapters that focus on various neuroprotective strategies and emerging therapeutic interventions for combating stroke pathophysiology. The chapters cover the role of stem cell therapy, the therapeutic effect of low-frequency electromagnetic radiations (LF-EMR), and implications of non-coding RNAs such as micro-RNAs as the biomarkers for diagnosis, prognosis, and therapy in ischemic stroke. 606 $aHuman physiology 606 $aNeurosciences 606 $aOxidative stress 606 $aRadiology 606 $aStem cells 606 $aNanotechnology 606 $aHuman Physiology$3https://scigraph.springernature.com/ontologies/product-market-codes/B13004 606 $aNeurosciences$3https://scigraph.springernature.com/ontologies/product-market-codes/B18006 606 $aOxidative Stress$3https://scigraph.springernature.com/ontologies/product-market-codes/L16070 606 $aDiagnostic Radiology$3https://scigraph.springernature.com/ontologies/product-market-codes/H29013 606 $aStem Cells$3https://scigraph.springernature.com/ontologies/product-market-codes/L16010 606 $aNanotechnology$3https://scigraph.springernature.com/ontologies/product-market-codes/Z14000 615 0$aHuman physiology. 615 0$aNeurosciences. 615 0$aOxidative stress. 615 0$aRadiology. 615 0$aStem cells. 615 0$aNanotechnology. 615 14$aHuman Physiology. 615 24$aNeurosciences. 615 24$aOxidative Stress. 615 24$aDiagnostic Radiology. 615 24$aStem Cells. 615 24$aNanotechnology. 676 $a612 702 $aPatnaik$b Ranjana$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aTripathi$b Amit Kumar$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aDwivedi$b Ashish$4edt$4http://id.loc.gov/vocabulary/relators/edt 906 $aBOOK 912 $a9910349465703321 996 $aAdvancement in the Pathophysiology of Cerebral Stroke$92184152 997 $aUNINA