LEADER 04898nam 22005535 450 001 9910349438803321 005 20250609110101.0 010 $a3-030-24285-4 024 7 $a10.1007/978-3-030-24285-5 035 $a(CKB)4100000009678305 035 $a(MiAaPQ)EBC5969454 035 $a(DE-He213)978-3-030-24285-5 035 $a(PPN)260303216 035 $a(MiAaPQ)EBC5969376 035 $a(EXLCZ)994100000009678305 100 $a20191030d2019 u| 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aHeat Shock Proteins in Neuroscience /$fedited by Alexzander A. A. Asea, Punit Kaur 205 $a1st ed. 2019. 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2019. 215 $a1 online resource (ix, 307 pages) $cillustrations 225 1 $aHeat Shock Proteins,$x1877-1246 ;$v20 300 $aIncludes index. 311 08$a3-030-24284-6 327 $aSection I: Neurological Aspects of HSP -- Chapter 1. Hsp60 Friend and Foe of the Nervous System -- Chapter 2. Role of Heat Shock Proteins in Brain Tumors -- Chapter 3. Body Temperature Regulation Determines Immune Reactions and Species Longevity -- Chapter 4. Interaction between Heat Shock Proteins and Components of the Plasminogen Activator System in the Central Nervous System -- Chapter 5. Role of HSP70 in Plasticity and Mem -- Chapter 6. Role of Heat Shock Proteins (HSP) in Neuroprotection for Ischemic Stroke -- Section II: Aspects of HSP in Neurodegenerative Diseases and Disorders -- Chapter 7. Dysregulation of Heat Shock Proteins in Neurodegenerative Diseases: Restorative Roles of Small Molecules and Natural Compounds -- Chapter 8. Molecular Chaperones and Protein Quality Control System in the Canine Model of Brain Aging and Neurodegenerative Diseases -- Chapter 9. Role of Hsp90 Interacting Molecular Chaperones on Tau And Aß Processing in Alzheimer?s Disease -- Section III: Aspects of HSP in Multiple Sclerosis -- Chapter 10. Role of Hsp70 in Multiple Sclerosis: An Overview -- Chapter 11. Protective Role of Glial Heat Shock Proteins in Amyotrophic Lateral Sclerosis -- Section IV: Development of HSP-Based Therapies for Neurological Disorders -- Chapter 12. Therapeutic Drugs and Natural Products: The Effect of Suppressing Hsps in Brain Tumors -- Chapter 13. Can HSP Targeted Gene Therapy be a New Hope for Gliomas? -- Chapter 14. Therapeutic Aspects of Heat Shock Proteins in Glioma: Cementing the Crevasses between Bench and Bedside -- Chapter 15. Engineering Chaperones for Alzheimer?s Disease: Insights from Drosophila Models -- Chapter 16. Role of HSP in the Treatment of Internal D?seases. 330 $aThe book Heat Shock Proteins in Neuroscience provides the most comprehensive review on contemporary knowledge on the role of HSP in signaling pathways relevant to a number of diseases. Using an integrative approach, the contributors provide a synopsis of novel mechanisms, signal transduction pathways. To enhance the ease of reading and comprehension, this book has been subdivided into various section including; Section I, reviews current progress on our understanding of Neurological Aspects of HSP; Section II, focuses on Aspects of HSP in Neurodegenerative Diseases and Disorders, Section III, emphasizes the importance of HSP in Multiple Sclerosis; Section IV, reviews critical Aspects of HSP in Alzheimer?s Disease and Section V, gives a comprehensive update of the Development of HSP-Based Therapies for Neurological Disorders. Key basic and clinical research laboratories from major universities, academic medical hospitals, biotechnology and pharmaceutical laboratories around the world have contributed chapters that review present research activity and importantly project the field into the future. The book is a must read for starters and professionals in the fields of Neurology and Neurosciences, Translational Medicine, Clinical Research, Human Physiology, Biotechnology, Cell & Molecular Medicine, Pharmaceutical Scientists and Researchers involved in Drug Discovery. 410 0$aHeat Shock Proteins,$x1877-1246 ;$v20 606 $aProteïnes$2thub 606 $aNeurociències$2thub 606 $aProtein Science$3https://scigraph.springernature.com/ontologies/product-market-codes/L14040 608 $aLlibres electrònics$2thub 615 7$aProteïnes. 615 7$aNeurociències. 615 14$aProtein Science. 676 $a572.6 676 $a572.6 702 $aAsea$b Alexzander A. A.$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aKaur$b Punit$4edt$4http://id.loc.gov/vocabulary/relators/edt 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910349438803321 996 $aHeat Shock Proteins in Neuroscience$91918772 997 $aUNINA