LEADER 03952nam 22007095 450 001 9910349438403321 005 20220518173335.0 010 $a3-030-28471-9 024 7 $a10.1007/978-3-030-28471-8 035 $a(CKB)4100000009678368 035 $a(MiAaPQ)EBC5968943 035 $a(DE-He213)978-3-030-28471-8 035 $a(PPN)258059303 035 $a(EXLCZ)994100000009678368 100 $a20191025d2019 u| 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aPluripotent Stem Cells in Eye Disease Therapy /$fedited by Kapil Bharti 205 $a1st ed. 2019. 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2019. 215 $a1 online resource (210 pages) 225 1 $aAdvances in Experimental Medicine and Biology,$x0065-2598 ;$v1186 311 $a3-030-28470-0 320 $aIncludes bibliographical references and index. 327 $aPluripotent Stem Cells to Model Degenerative Retinal Diseases: The RPE perspective -- Utility of induced pluripotent stem cell-derived retinal pigment epithelium for an in vitro model of proliferative vitreoretinopathy -- Developing cell-based therapies for RPE-associated degenerative eye diseases -- Pluripotent Stem Cell derived 3D Ocular Tissue Transplantation ? role of immune system in cell integration -- Use of Stem Cells to model optic nerve degeneration diseases -- Surgical approaches for RPE/retina -- 3D Engineering Ocular Tissues for Disease Modeling and Drug Testing -- Index. 330 $aThis book discusses applications of pluripotent stem cells to study eye disease in vitro and to create novel therapies for degenerative eye diseases. Chapters are contributed by experts in the field and cover such topics as the use of pluripotent stem cells in 2D and 3D engineering of ocular tissues for disease modelling and drug testing as well as approaches to replace degenerated RPE and photoreceptors in macular degeneration and retinitis pigmentosa. Pluripotent Stem Cells in Eye Disease Therapy presents a comprehensive discussion of basic science and clinical applications and is an indispensable resource for everyone from advanced graduate students to advanced professionals who want to learn about the potential of stem cell biology and its role in the field of retinal diseases. . 410 0$aAdvances in Experimental Medicine and Biology,$x0065-2598 ;$v1186 606 $aStem cells 606 $aRegenerative medicine 606 $aTissue engineering 606 $aBiomedical engineering 606 $aOphthalmology 606 $aStem Cells$3https://scigraph.springernature.com/ontologies/product-market-codes/L16010 606 $aRegenerative Medicine/Tissue Engineering$3https://scigraph.springernature.com/ontologies/product-market-codes/L16080 606 $aBiomedical Engineering/Biotechnology$3https://scigraph.springernature.com/ontologies/product-market-codes/B24000 606 $aOphthalmology$3https://scigraph.springernature.com/ontologies/product-market-codes/H44004 606 $aOftalmopaties$2thub 606 $aCèl·lules mare$2thub 608 $aLlibres electrònics$2thub 615 0$aStem cells. 615 0$aRegenerative medicine. 615 0$aTissue engineering. 615 0$aBiomedical engineering. 615 0$aOphthalmology. 615 14$aStem Cells. 615 24$aRegenerative Medicine/Tissue Engineering. 615 24$aBiomedical Engineering/Biotechnology. 615 24$aOphthalmology. 615 7$aOftalmopaties 615 7$aCèl·lules mare 676 $a616.02774 702 $aBharti$b Kapil$4edt$4http://id.loc.gov/vocabulary/relators/edt 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910349438403321 996 $aPluripotent Stem Cells in Eye Disease Therapy$92280551 997 $aUNINA