LEADER 01055nam0-22003131i-450- 001 990000114560403321 005 20070611095320.0 035 $a000011456 035 $aFED01000011456 035 $a(Aleph)000011456FED01 035 $a000011456 100 $a20020821d1908----km-y0itay50------ba 101 0 $aita 102 $aIT 105 $ay-------001yy 200 1 $aRelazione$fComitato centrale disoccorso pei danneggiati dal terremoto del 28 dicembre 1908 in Calabria ed in Sicilia 210 $aRoma$cTipografia della Camera dei deputati$d[1908?] 215 $aCLXXIII, 686 p., 12 tav.$cill.$d29 cm 610 0 $aSicilia$aTerremoto 1908$aAssistenza 610 0 $aCalabria$aTerremoto 1908$aAssistenza 676 $a363.349 710 01$aComitato centrale di soccorso pei danneggiati dal terremoto del 28 dicembre 1908 in Calabria ed in Sicilia$0427711 801 0$aIT$bUNINA$gRICA$2UNIMARC 901 $aBK 912 $a990000114560403321 952 $a13 M 26 32$b42$fFINBC 959 $aFINBC 996 $aRelazione$9115310 997 $aUNINA LEADER 04890nam 22005895 450 001 9910349375603321 005 20200702122749.0 010 $a3-030-21540-7 024 7 $a10.1007/978-3-030-21540-8 035 $a(CKB)4100000008878248 035 $a(MiAaPQ)EBC5847401 035 $a(DE-He213)978-3-030-21540-8 035 $a(PPN)258061227 035 $a(EXLCZ)994100000008878248 100 $a20190805d2019 u| 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aHepatocellular Carcinoma $eTranslational Precision Medicine Approaches /$fedited by Yujin Hoshida 205 $a1st ed. 2019. 210 1$aCham :$cSpringer International Publishing :$cImprint: Humana,$d2019. 215 $a1 online resource (365 pages) 225 1 $aMolecular and Translational Medicine,$x2197-7852 311 $a3-030-21539-3 327 $aPart 1: Clinical demographics and management -- 1. Risk Factors of Hepatocellular Carcinoma for Precision Personalized Care -- 2. Hepatocellular Carcinoma Surveillance and Staging -- 3. Changing Epidemiology of Hepatocellular Carcinoma and Role of Surveillance -- Part 2: Diagnosis and prognostication -- 4. Radiological diagnosis and characterization of HCC -- 5. Analysis of Hepatocellular Carcinoma Tissue for Biomarker and Therapeutic Target Discovery -- 6. Molecular subtypes and genomic signatures of hepatocellular carcinoma for prognostication and therapeutic decision making -- 7. Liquid Biopsy in Hepatocellular Carcinoma -- Part 3: Treatment -- 8. Surgical Therapies in Hepatocellular Carcinoma -- 9. Interventional Radiologic Therapies for Hepatocellular Carcinoma: From Where We Began To Where We Are Going -- 10. Precision Locoregional Therapies for Hepatocellular Carcinoma: Percutaneous Ablation and Radiotherapy -- 11. Molecular-targeted therapies in hepatocellular carcinoma -- 12. Immune therapies -- 13. Prevention Strategies for Hepatocellular Carcinoma -- Part 4: Molecular pathogenesis and therapeutic discovery -- 14. Molecular Alterations and Heterogeneity in Hepatocellular Carcinoma -- 15. Stromal and Immune Drivers of Hepatocarcinogenesis -- 16. Experimental Models for Preclinical Research in Hepatocellular Carcinoma. 330 $aThis book provides a comprehensive overview of the current limitations and unmet needs in Hepatocellular Carcinoma (HCC) diagnosis, treatment, and prevention. It also provides newly emerging concepts, approaches, and technologies to address challenges. Topics covered include changing landscape of HCC etiologies in association with health disparities, framework of clinical management algorithm, new and experimental modalities of HCC diagnosis and prognostication, multidisciplinary treatment options including rapidly evolving molecular targeted therapies and immune therapies, multi-omics molecular characterization, and clinically relevant experimental models. The book is intended to assist collaboration between the diverse disciplines and facilitate forward and reverse translation between basic and clinical research by providing a comprehensive overview of relevant areas, covering epidemiological trend and population-level patient management strategies, new diagnostic and prognostic tools, recent advances in the standard care and novel therapeutic approaches, and new concepts in pathogenesis and experimental approaches and tools, by experts and opinion leaders in their respective fields. By thoroughly and concisely covering whole aspects of HCC care, Hepatocellular Carcinoma serves as a valuable reference for multidisciplinary readers, and promotes the development of personalized precision care strategies that lead to substantial improvement of disease burden and patient prognosis in HCC. 410 0$aMolecular and Translational Medicine,$x2197-7852 606 $aPathology 606 $aOncology   606 $aGastroenterology  606 $aHepatology 606 $aPathology$3https://scigraph.springernature.com/ontologies/product-market-codes/H4800X 606 $aOncology$3https://scigraph.springernature.com/ontologies/product-market-codes/H33160 606 $aGastroenterology$3https://scigraph.springernature.com/ontologies/product-market-codes/H33061 606 $aHepatology$3https://scigraph.springernature.com/ontologies/product-market-codes/H33088 615 0$aPathology. 615 0$aOncology  . 615 0$aGastroenterology . 615 0$aHepatology. 615 14$aPathology. 615 24$aOncology. 615 24$aGastroenterology. 615 24$aHepatology. 676 $a616.99436 676 $a616.99436 702 $aHoshida$b Yujin$4edt$4http://id.loc.gov/vocabulary/relators/edt 906 $aBOOK 912 $a9910349375603321 996 $aHepatocellular Carcinoma$91735056 997 $aUNINA