LEADER 04574nam 22006495 450 001 9910349295003321 005 20200705013413.0 010 $a94-007-6727-7 024 7 $a10.1007/978-94-007-6727-0 035 $a(CKB)3710000000499569 035 $a(DE-He213)978-94-007-6727-0 035 $a(PPN)242975534 035 $a(EXLCZ)993710000000499569 100 $a20190617d2020 u| 0 101 0 $aeng 135 $aurnn|008mamaa 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aEvolution of Venomous Animals and Their Toxins$b[electronic resource] /$fedited by P. Gopalakrishnakone, Anita Malhotra 210 1$aDordrecht :$cSpringer Netherlands :$cImprint: Springer,$d2020. 215 $a1 online resource (Approx. 550 p. 30 illus., 15 illus. in color.) 225 1 $aToxinology,$x2542-761X 327 $aA Critique of the Toxicoferan Hypothesis -- Evolution of Resistance to Toxins in Prey -- Evolution of Separate Predation- and Defence-Evoked Venoms in Carnivorous Cone Snails -- Evolutionary Context of Venom in Animals -- Functional and Genetic Diversity of Toxins in Sea Anemones -- Independent Origins of Scorpion Toxins Affecting Potassium and Sodium Channels -- Mutation, Duplication, and More in the Evolution of Venomous Animals and Their Toxins -- Parasitoid Wasps and Their Venoms -- The Strategic Use of Venom by Spiders -- Toxicity in Cephalopods -- Venom Use in Mammals: Evolutionary Aspects -- Venom as a Component of External Immune Defense in Hymenoptera -- Phylogeny of Annelida -- Systematics and Evolution of the Conoidea -- Systematics of Cephalopods -- Systematics of Siphonophores -- Evolution of the Snake Venom Delivery System -- Evolution, Morphology and Development of the Centipede Venom System -- Evolutionary History of Venom Glands in the Siluriformes. 330 $aIn recent years, the field of Toxinology has expanded substantially. On the one hand it studies venomous animals, plants and micro organisms in detail to understand their mode of action on targets. While on the other, it explores the biochemical composition, genomics and proteomics of toxins and venoms to understand their three interaction with life forms (especially humans), development of antidotes and exploring their pharmacological potential. Therefore, Toxinology has deep linkages with biochemistry, molecular biology, anatomy and pharmacology. In addition, there is a fast developing applied subfield, clinical toxinology, which deals with understanding and managing medical effects of toxins on human body. Given the huge impact of toxin-based deaths globally, and the potential of venom in generation of drugs for so-far incurable diseases (for example, Diabetes, Chronic Pain), the continued research and growth of the field is imminent. This has led to the growth of research in the area and the consequent sc. 410 0$aToxinology,$x2542-761X 606 $aMedicine 606 $aPharmacology 606 $aPharmaceutical technology 606 $aLife sciences 606 $aBiochemistry 606 $aAnimal physiology 606 $aBiomedicine, general$3https://scigraph.springernature.com/ontologies/product-market-codes/B0000X 606 $aPharmacology/Toxicology$3https://scigraph.springernature.com/ontologies/product-market-codes/B21007 606 $aPharmaceutical Sciences/Technology$3https://scigraph.springernature.com/ontologies/product-market-codes/B21010 606 $aLife Sciences, general$3https://scigraph.springernature.com/ontologies/product-market-codes/L00004 606 $aAnimal Biochemistry$3https://scigraph.springernature.com/ontologies/product-market-codes/L14013 606 $aAnimal Physiology$3https://scigraph.springernature.com/ontologies/product-market-codes/L33030 615 0$aMedicine. 615 0$aPharmacology. 615 0$aPharmaceutical technology. 615 0$aLife sciences. 615 0$aBiochemistry. 615 0$aAnimal physiology. 615 14$aBiomedicine, general. 615 24$aPharmacology/Toxicology. 615 24$aPharmaceutical Sciences/Technology. 615 24$aLife Sciences, general. 615 24$aAnimal Biochemistry. 615 24$aAnimal Physiology. 676 $a610 702 $aGopalakrishnakone$b P$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aMalhotra$b Anita$4edt$4http://id.loc.gov/vocabulary/relators/edt 906 $aBOOK 912 $a9910349295003321 996 $aEvolution of Venomous Animals and Their Toxins$92079007 997 $aUNINA