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H. Mathews and Leila Jamal, Revisiting Respect for Persons in Genomic Research -- Reprinted from: Genes 2014, 5(1), 1-12 http://www.mdpi.com/2073-4425/5/1/1 1 -- Vincent Timmerman, Alleene V. Strickland and Stephan Zu?chner -- Genetics of Charcot-Marie-Tooth (CMT) Disease within the Frame of the Human Genome Project Success -- Reprinted from: Genes 2014, 5(1), 13-32 http://www.mdpi.com/2073-4425/5/1/13 13 -- Megan E. Aldrup-MacDonald and Beth A. Sullivan -- The Past, Present, and Future of Human Centromere Genomics -- Reprinted from: Genes 2014, 5(1), 33-50 -- http://www.mdpi.com/2073-4425/5/1/33 32 -- Nathalie Chami and Guillaume Lettre -- Lessons and Implications from Genome-Wide Association Studies (GWAS) Findings of Blood Cell Phenotypes -- Reprinted from: Genes 2014, 5(1), 51-64 -- http://www.mdpi.com/2073-4425/5/1/51 49 -- Jose Russo, Julia Santucci-Pereira and Irma H. Russo -- The Genomic Signature of Breast Cancer Prevention -- Reprinted from: Genes 2014, 5(1), 65-83 -- http://www.mdpi.com/2073-4425/5/1/65 63 -- IV -- Katsushi Tokunaga -- Lessons from Genome-Wide Search for Disease-Related Genes with Special Reference to HLA-Disease Associations -- Reprinted from: Genes 2014, 5(1), 84-96 -- http://www.mdpi.com/2073-4425/5/1/84 82 -- Hannelore Ehrenreich and Klaus-Armin Nave Phenotype-Based Genetic Association Studies (PGAS)-Towards Understanding the Contribution of Common Genetic Variants to Schizophrenia Subphenotypes -- Reprinted from: Genes 2014, 5(1), 97-105 -- http://www.mdpi.com/2073-4425/5/1/97 95 -- Albino Bacolla, David N. Cooper and Karen M. Vasquez -- Mechanisms of Base Substitution Mutagenesis in Cancer Genomes --Reprinted from: Genes 2014, 5(1), 108-146 -- http://www.mdpi.com/2073-4425/5/1/108 104 -- Muhammad Imran Khan, Maleeha Azam, Muhammad Ajmal, Rob W. J. Collin, Anneke I. den Hollander, Frans P. M. Cremers and Raheel Qamar -- The Molecular Basis of Retinal Dystrophies in Pakistan -- Reprinted from: Genes 2014, 5(1), 176-195 -- http://www.mdpi.com/2073-4425/5/1/176 144 -- Sara L. Pulit, Maarten Leusink, Androniki Menelaou and Paul I. W. de Bakker -- Association Claims in the Sequencing Era -- Reprinted from: Genes 2014, 5(1), 196-213 -- http://www.mdpi.com/2073-4425/5/1/196 163 -- Megan J. Puckelwartz and Elizabeth M. McNally -- Genetic Profiling for Risk Reduction in Human Cardiovascular Disease -- Reprinted from: Genes 2014, 5(1), 214-234 -- http://www.mdpi.com/2073-4425/5/1/214 181 -- David J. Elliott -- Illuminating the Transcriptome through the Genome -- Reprinted from: Genes 2014, 5(1), 235-253 -- http://www.mdpi.com/2073-4425/5/1/235 203 -- V -- Nicola Whiffin and Richard S. Houlston -- Architecture of Inherited Susceptibility to Colorectal Cancer: A Voyage of Discovery -- Reprinted from: Genes 2014, 5(2), 270-284 -- http://www.mdpi.com/2073-4425/5/2/270 222 -- Dianne F. Newbury, Anthony P. Monaco and Silvia Paracchini -- Reading and Language Disorders: The Importance of Both Quantity and Quality -- Reprinted from: Genes 2014, 5(2), 285-309 -- http://www.mdpi.com/2073-4425/5/2/285 237. 330 $aIn 1990, scientists began working together on one of the largest biological research projects ever proposed. The project proposed to sequence the three billion nucleotides in the human genome. The Human Genome Project took 13 years and was completed in April 2003, at a cost of approximately three billion dollars. It was a major scientific achievement that forever changed the understanding of our own nature. The sequencing of the human genome was in many ways a triumph for technology as much as it was for science. From the Human Genome Project, powerful technologies have been developed (e.g., microarrays and next generation sequencing) and new branches of science have emerged (e.g., functional genomics and pharmacogenomics), paving new ways for advancing genomic research and medical applications of genomics in the 21st century. The investigations have provided new tests and drug targets, as well as insights into the basis of human development and diagnosis/treatment of cancer and several mysterious humans diseases. This genomic revolution is prompting a new era in medicine, which brings both challenges and opportunities. Parallel to the promising advances over the last decade, the study of the human genome has also revealed how complicated human biology is, and how much remains to be understood. The legacy of the understanding of our genome has just begun. To celebrate the 10th anniversary of the essential completion of the Human Genome Project, in April 2013 Genes launched this Special Issue, which highlights the recent scientific breakthroughs in human genomics, with a collection of papers written by authors who are leading experts in the field. 517 $aGrand Celebration 606 $aHuman gene mapping 615 0$aHuman gene mapping. 676 $a599.935 801 0$bNjHacI 801 1$bNjHacl 906 $aBOOK 912 $a9910598027503321 996 $aGrand Celebration$93015889 997 $aUNINA LEADER 02904nam 2200673z- 450 001 9910346955603321 005 20210211 010 $a1000080517 035 $a(CKB)4920000000100966 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/53715 035 $a(oapen)doab53715 035 $a(EXLCZ)994920000000100966 100 $a20202102d2018 |y 0 101 0 $ager 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aModellentwicklung eines ganzheitlichen Projektmanagementsystems fu?r kerntechnische Ru?ckbauprojekte (MogaMaR) : Schlussbericht des Forschungsvorhabens 210 $cKIT Scientific Publishing$d2018 215 $a1 online resource (IX, 180 p. p.) 225 1 $aProduktion und Energie / Karlsruher Institut für Technologie, Institut für Industriebetriebslehre und industrielle Produktion u. Deutsch-Französisches Institut für Umweltforschung 311 08$a3-7315-0762-5 330 $aThe development of a holistic and integrated project management and planning system is crucial to avoid deviations from the plan and to consider uncertainties in the planning stage of nuclear dismantling projects. Therefore, in the research project MogaMaR characteristics of such projects as well as shortcomings in the current project management were identified. On the basis of these findings, a holistic project management system for nuclear dismantling projects was developed. 606 $aSchlussbericht$2gnd 606 $aDismantling of nuclear facilities 606 $aPlanung Rückbau$2gnd 606 $aFinal report$2gnd 606 $aProjekt management system$2gnd 606 $aRückbau kerntechnischer Anlagen$2gnd 606 $aProject management 606 $aProject management$vSoftware 606 $aProjektmanagement$2gnd 606 $aPlanning of deconstruction 615 7$aSchlussbericht 615 0$aDismantling of nuclear facilities 615 7$aPlanung Rückbau 615 7$aFinal report 615 7$aProjekt management system 615 7$aRückbau kerntechnischer Anlagen 615 0$aProject management. 615 0$aProject management 615 7$aProjektmanagement. 615 0$aPlanning of deconstruction 700 $aHübner$b Felix$4auth$01771360 702 $aVolk$b Rebecca$4auth 702 $aSecer$b Oktay$4auth 702 $aKuhn$b Daniel$f1975-$4auth 702 $aSahre$b Peter$4auth 702 $aKnappik$b Reinhard$4auth 702 $aSchultmann$b Frank$4auth 702 $aGentes$b Sascha$4auth 702 $avon Both$b Petra$4auth 801 0$bMiAaPQ 801 2$bNZ-WeVUL 906 $aBOOK 912 $a9910346955603321 996 $aModellentwicklung eines ganzheitlichen Projektmanagementsystems für kerntechnische Rückbauprojekte (MogaMaR)$94258457 997 $aUNINA