LEADER 01970nam 2200397z- 450 001 9910346902703321 005 20210211 010 $a1000023886 035 $a(CKB)4920000000101495 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/54079 035 $a(oapen)doab54079 035 $a(EXLCZ)994920000000101495 100 $a20202102d2011 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aMultiscale Modeling of the Ventricles: From Cellular Electrophysiology to Body Surface Electrocardiograms 210 $cKIT Scientific Publishing$d2011 215 $a1 online resource (XIII, 248 p. p.) 225 1 $aKarlsruhe transactions on biomedical engineering / Ed.: Karlsruhe Institute of Technology / Institute of Biomedical Engineering 311 08$a3-86644-714-0 330 $aThis work is focused on different aspects within the loop of multiscale modeling:On the cellular level, effects of adrenergic regulation and the Long-QT syndrome have been investigated.On the organ level, a model for the excitation conduction system was developed and the role of electrophysiological heterogeneities was analyzed.On the torso level a dynamic model of a deforming heart was created and the effects of tissue conductivities on the solution of the forward problem were evaluated. 517 $aMultiscale Modeling of the Ventricles 606 $aTechnology: general issues$2bicssc 610 $aCardiac Electrophysiology 610 $aElectrophysiological Heterogeneities 610 $aForward Calculation 610 $aMultiscale Modeling 615 7$aTechnology: general issues 700 $aKeller$b David Urs Josef$4auth$01313351 906 $aBOOK 912 $a9910346902703321 996 $aMultiscale Modeling of the Ventricles: From Cellular Electrophysiology to Body Surface Electrocardiograms$93031319 997 $aUNINA