LEADER 02560nam 2200349 450 001 9910688469503321 005 20230623210918.0 010 $a3-03842-990-2 035 $a(CKB)5400000000000144 035 $a(NjHacI)995400000000000144 035 $a(EXLCZ)995400000000000144 100 $a20230623d2018 uy 0 101 0 $aeng 135 $aur||||||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aCyclic Nucleotide Signaling and the Cardiovascular System /$fedited by Thomas Brand, Enno Klussmann 210 1$aBasel :$cMDPI,$d2018. 215 $a1 online resource (306 pages) 330 $aThe cyclic nucleotides 3',5'-adenosine monophosphate (cAMP) and 3',5'-cyclic guanosine monophosphate (cGMP) play important roles in the control of cardiovascular function under physiological and pathological conditions. In this book, which is a reprint of a Special Issue of the Journal of Cardiovascular Development and Disease entitled "Cyclic Nucleotide Signaling and the Cardiovascular System", internationally recognized experts give an overview of this vibrant scientific field. The first series of articles deal with the localization and function of membrane-bound and soluble adenylate cyclases, followed by articles on the roles of phosphodiesterase isoforms in the heart. Cyclic nucleotide signaling takes place in nanodomains and the A-kinase anchor proteins (AKAPS) are essential for the compartmentalized assembly of signaling proteins into functional complexes. Reviews on the role of AKAP proteins in the physiology and pathophysiology of the heart are also included in this book. Cyclic nucleotides act through effector proteins and articles on EPAC and POPDC proteins inform the reader of recent developments on these topics. A major advancement in our understanding of cyclic nucleotide signaling came through the use of genetically encoded cAMP sensor molecules, and a series of articles review the current insight that these reporter molecules have provided. The final set of articles in this book deals with the association of the cyclic nucleotide pathway and cardiovascular disease as well as the development of novel therapeutic approaches. 606 $aNucleotides 615 0$aNucleotides. 676 $a547.79 702 $aKlussmann$b Enno 702 $aBrand$b Thomas 801 0$bNjHacI 801 1$bNjHacl 906 $aBOOK 912 $a9910688469503321 996 $aCyclic Nucleotide Signaling and the Cardiovascular System$92943092 997 $aUNINA LEADER 02272oam 2200505 450 001 9910707808003321 005 20171106153454.0 035 $a(CKB)5470000002468483 035 $a(OCoLC)968130016 035 $a(EXLCZ)995470000002468483 100 $a20170110d2016 ua 0 101 0 $aeng 135 $aurbn||||a|||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aHearing on National Defense Authorization Act for Fiscal Year 2017 and oversight of previously authorized programs before the Committee on Armed Services, House of Representatives, One Hundred Fourteenth Congress, second session $eSubcommittee on Seapower and Projection Forces hearing on logistics and sealift force requirements : hearing held March 22, 2016 210 1$aWashington, D.C. :$cU.S. Government Publishing Office,$d2016. 215 $a1 online resource (iii, 65 pages) 300 $aPaper version available for sale by the Superintendent of Documents, United States Government Publishing Office. 300 $a"H.A.S.C. no. 114-116." 517 $aHearing on National Defense Authorization Act for Fiscal Year 2017 and oversight of previously authorized programs before the Committee on Armed Services, House of Representatives, One Hundred Fourteenth Congress, second session 606 $aTransportation, Military$zUnited States 606 $aMilitary sealift$zUnited States 606 $aCombat sustainability (Military science) 606 $aMerchant ships$zUnited States 606 $aLogistics 608 $aLegislative hearings.$2lcgft 615 0$aTransportation, Military 615 0$aMilitary sealift 615 0$aCombat sustainability (Military science) 615 0$aMerchant ships 615 0$aLogistics. 801 0$bGPO 801 1$bGPO 801 2$bGPO 801 2$bMERUC 801 2$bOCLCF 801 2$bIOG 801 2$bGPO 801 2$bOCLCQ 906 $aBOOK 912 $a9910707808003321 996 $aHearing on National Defense Authorization Act for Fiscal Year 2017 and oversight of previously authorized programs before the Committee on Armed Services, House of Representatives, One Hundred Fourteenth Congress, second session$93436327 997 $aUNINA LEADER 01922nam 2200421z- 450 001 9910557250303321 005 20211118 035 $a(CKB)5400000000041445 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/73997 035 $a(oapen)doab73997 035 $a(EXLCZ)995400000000041445 100 $a20202111d2020 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$a10 Years of Inflammation Pharmacology 210 $cFrontiers Media SA$d2020 215 $a1 online resource (215 p.) 311 08$a2-88963-857-X 330 $aThis eBook is a collection of articles from a Frontiers Research Topic. 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Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact 606 $aPharmacology$2bicssc 606 $aScience: general issues$2bicssc 610 $aanti-inflammatory agents 610 $aInflammation 610 $aInflammation Pharmacology 610 $ainflammatory responses 610 $aleukocyte 610 $aPharmacology 615 7$aPharmacology 615 7$aScience: general issues 700 $aPatrignani and Dieter Steinhilber$b Paola$4edt$01312943 702 $aPatrignani and Dieter Steinhilber$b Paola$4oth 906 $aBOOK 912 $a9910557250303321 996 $a10 Years of Inflammation Pharmacology$93031154 997 $aUNINA LEADER 01739nam 2200397z- 450 001 9910346899603321 005 20210211 010 $a1000024937 035 $a(CKB)4920000000101526 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/45216 035 $a(oapen)doab45216 035 $a(EXLCZ)994920000000101526 100 $a20202102d2011 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aDirect Radiative Effects of Sea Salt on the Regional Scale 210 $cKIT Scientific Publishing$d2011 215 $a1 online resource (V, 242 p. p.) 225 1 $aWissenschaftliche Berichte des Instituts für Meteorologie und Klimaforschung des Karlsruher Instituts für Technologie 311 08$a3-86644-773-6 330 $aThis thesis aims to quantify the direct radiative effects of sea salt aerosol in the atmosphere. The online coupled regional scale model system COSMO-ART is extended for this objective with respect to the sea salt aerosol. Furthermore, a new sea salt optical parameterisation is developed for both the shortwave and longwave spectrum. Based on numerical simulations with the extended model system, the direct radiative effects of sea salt aerosol are investigated. 606 $aPhysics$2bicssc 610 $aCOSMO-ART 610 $adirect radiative effects 610 $anumerical modelling 610 $aregional scale 610 $asea salt aerosol 615 7$aPhysics 700 $aLundgren$b Kristina$4auth$01327813 906 $aBOOK 912 $a9910346899603321 996 $aDirect Radiative Effects of Sea Salt on the Regional Scale$93038129 997 $aUNINA