LEADER 02054nam 2200409z- 450 001 9910346863503321 005 20210211 010 $a1-000-03536-0 035 $a(CKB)4920000000101881 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/54078 035 $a(oapen)doab54078 035 $a(EXLCZ)994920000000101881 100 $a20202102d2013 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aMultiscale Modeling of Cardiac Electrophysiology: Adaptation to Atrial and Ventricular Rhythm Disorders and Pharmacological Treatment 210 $cKIT Scientific Publishing$d2013 215 $a1 online resource (IX, 181 p. p.) 225 1 $aKarlsruhe transactions on biomedical engineering / Ed.: Karlsruhe Institute of Technology / Institute of Biomedical Engineering 311 08$a3-7315-0045-0 330 $aMultiscale modeling of cardiac electrophysiology helps to better understand the underlying mechanisms of atrial fibrillation, acute cardiac ischemia and pharmacological treatment. For this purpose, measurement data reflecting these conditions have to be integrated into models of cardiac electrophysiology. Several methods for this model adaptation are introduced in this thesis. The resulting effects are investigated in multiscale simulations ranging from the ion channel up to the body surface. 517 $aMultiscale Modeling of Cardiac Electrophysiology 606 $aTechnology: general issues$2bicssc 610 $aacute cardiac ischemia 610 $aatrial fibrillation 610 $acardiac modeling 610 $aparameter adaptation 610 $apharmacological therapy 615 7$aTechnology: general issues 700 $aWilhelms$b Mathias$4auth$01290852 906 $aBOOK 912 $a9910346863503321 996 $aMultiscale Modeling of Cardiac Electrophysiology: Adaptation to Atrial and Ventricular Rhythm Disorders and Pharmacological Treatment$93021659 997 $aUNINA