LEADER 04927nam 2201465z- 450 001 9910346847303321 005 20231214133654.0 010 $a3-03921-188-9 035 $a(CKB)4920000000095167 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/42231 035 $a(EXLCZ)994920000000095167 100 $a20202102d2019 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aBiological Potential and Medical Use of Secondary Metabolites 210 $cMDPI - Multidisciplinary Digital Publishing Institute$d2019 215 $a1 electronic resource (284 p.) 311 $a3-03921-187-0 330 $aMany macro and micro species, from terrestrial and aquatic environments, produce structurally unique compounds and, in many countries, still are the primary sources of medicines. In fact, secondary metabolites are an important source of chemotherapeutic agents but are also lead compounds for synthetic modification and the optimization of biological activity. Therefore, the exploitation of secondary metabolites, or their inspired synthetic compounds, offers excellent opportunities for the pharmaceutical industry. This Medicines Special Issue focuses on the great potential of secondary metabolites for therapeutic application. The Special Issue contains 16 articles reporting relevant experimental results, and an overview of bioactive secondary metabolites, their biological effects, and new methodologies that improve and accelerate the process of obtained lead compounds with regard to new drug development. We would like to thank all 83 authors, from all over the world, for their valuable contributions to this Special Issue. 610 $aantitumor 610 $atriterpenoids 610 $aseaweeds 610 $aditerpenes 610 $aBoswellia 610 $aantioxidant activity 610 $aantiplasmodial 610 $aMaytenus chiapensis 610 $aphenolic derivatives 610 $asecondary metabolites 610 $amedicinal applications 610 $aMalus x domestica 610 $apectin 610 $acytotoxic activity 610 $axanthine oxidase 610 $aphytochemistry 610 $aantioxidant 610 $aScabiosa 610 $asugars 610 $asargaquinoic acid 610 $apentacyclic triterpenoids 610 $aanalysis 610 $aantimicrobial and anticancer activity 610 $airidoids 610 $aTuscany 610 $aGC-MS 610 $a(-)-rabdosiin 610 $akratom 610 $aplant defense 610 $acembranoids 610 $atingenone 610 $adeoxypodophyllotoxin 610 $aanticancer 610 $apristimerin 610 $ainflammation 610 $aboswellic acids 610 $aplants 610 $aanti-inflammatory 610 $alegalization 610 $aMitragyna speciosa 610 $aOcimum sanctum 610 $acordycepin 610 $acytotoxic 610 $amedicine 610 $aArtemisia species 610 $aantimicrobial activity 610 $alignans 610 $aArtemisia vachanica 610 $aCordyceps militaris 610 $afrankincense 610 $aancient varieties 610 $asargahydroquinoic acid 610 $aTajikistan 610 $aantiSMASH 610 $aABTS 610 $apolyphenols 610 $atherapeutics 610 $ainfectious diseases 610 $aantibacterial 610 $anutraceutics 610 $atotal phenolics 610 $aLC-MS/MS 610 $ainnate immunity 610 $aHPLC-PAD 610 $asarganaphthoquinoic acid 610 $abiosynthetic gene clusters 610 $aDPPH 610 $aEGCG 610 $acneorubenoids 610 $aPPAR-? 610 $abowel diseases 610 $aamentoflavone 610 $amolecular docking 610 $asargachromenoic acid 610 $acannabinoids 610 $aflavonoids 610 $aessential oils 610 $aTCM 610 $aHPLC-PDA 610 $aascorbic acid 610 $aantioxidants 610 $aLamiaceae 610 $ananoemulsion 610 $amalaria 610 $atherapeutic uses 610 $aquinonemethide triterpenoids 610 $aartemisinin 610 $anatural products 610 $abiological activities 610 $aFRAP 610 $atoxicology 610 $adefensins 610 $aCelastraceae 610 $acannabis 610 $avector control 610 $aJuniperus 610 $aanalytical determination 700 $aSeca$b Ana M. L$4auth$01292427 702 $aPinto$b Diana Cláudia$4auth 906 $aBOOK 912 $a9910346847303321 996 $aBiological Potential and Medical Use of Secondary Metabolites$93022294 997 $aUNINA