LEADER 02053nam 2200445z- 450 001 9910346771003321 005 20210211 010 $a1000054615 035 $a(CKB)4920000000100813 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/53693 035 $a(oapen)doab53693 035 $a(EXLCZ)994920000000100813 100 $a20202102d2016 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aModeling Human Atrial Patho-Electrophysiology from Ion Channels to ECG - Substrates, Pharmacology, Vulnerability, and P-Waves 210 $cKIT Scientific Publishing$d2016 215 $a1 online resource (IX, 318 p. p.) 225 1 $aKarlsruhe transactions on biomedical engineering / Ed.: Karlsruhe Institute of Technology / Institute of Biomedical Engineering 311 08$a3-7315-0528-2 330 $aHalf of the patients suffering from atrial fibrillation (AF) cannot be treated adequately, today. This book presents multi-scale computational methods to advance our understanding of patho-mechanisms, to improve the diagnosis of patients harboring an arrhythmogenic substrate, and to tailor therapy. The modeling pipeline ranges from ion channels on the subcellular level up to the ECG on the body surface. The tailored therapeutic approaches carry the potential to reduce the burden of AF. 606 $aTechnology: general issues$2bicssc 610 $aatria 610 $aatrial fibrillation 610 $aComputermodell 610 $aelectrophysiology 610 $aElektrophysiologie 610 $aP-wave 610 $aP-Welle 610 $aVorhof 610 $aVorhofflimmerncomputational modeling 615 7$aTechnology: general issues 700 $aLoewe$b Axel$4auth$01272017 906 $aBOOK 912 $a9910346771003321 996 $aModeling Human Atrial Patho-Electrophysiology from Ion Channels to ECG - Substrates, Pharmacology, Vulnerability, and P-Waves$93031681 997 $aUNINA