LEADER 02451nam 2200385z- 450 001 9910346749803321 005 20231214133401.0 035 $a(CKB)4920000000094216 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/40385 035 $a(EXLCZ)994920000000094216 100 $a20202102d2018 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aAdverse Effects of Cancer Chemotherapy: Anything New to Improve Tolerance and Reduce Sequelae? 210 $cFrontiers Media SA$d2018 215 $a1 electronic resource (245 p.) 225 1 $aFrontiers Research Topics 311 $a2-88945-482-7 330 $aAdvances in anti-cancer chemotherapy over recent years have led to improved efficacy in curing or controlling many cancers. Some chemotherapy-related side-effects are well recognized and include: nausea, vomiting, bone marrow suppression, peripheral neuropathy, cardiac and skeletal muscle dysfunction and renal impairment. However, it is becoming clearer that some chemotherapy-related adverse effects may persist even in long term cancer survivors. Problems such as cognitive, cardiovascular and gastrointestinal dysfunction, and neuropathy may lead to substantial long term morbidity. Despite improvements in treatments to counteract acute chemotherapy-induced adverse effects, they are often incompletely effective. Furthermore, counter-measures for some acute side-effects and many potential longer term sequelae of anti-cancer chemotherapy have not been developed. Thus, new insights into prevalence and mechanisms of cancer chemotherapy-related side effects are needed and new approaches to improving tolerance and reduce sequelae of cancer chemotherapy are urgently needed. The present Research Topic focuses on adverse effects and sequelae of chemotherapy and strategies to counteract them. 517 $aAdverse Effects of Cancer Chemotherapy 610 $atoxicity 610 $acancer treatment 610 $aantineoplastic drugs 610 $aadverse effects 610 $achemotherapy 700 $aR. Thomas Jagoe$4auth$01292411 702 $aKulmira Nurgali$4auth 702 $aRaquel Abalo$4auth 906 $aBOOK 912 $a9910346749803321 996 $aAdverse Effects of Cancer Chemotherapy: Anything New to Improve Tolerance and Reduce Sequelae$93022278 997 $aUNINA