LEADER 02959nam 2200409z- 450 001 9910346747603321 005 20231214133600.0 035 $a(CKB)4920000000094238 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/53853 035 $a(EXLCZ)994920000000094238 100 $a20202102d2018 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aMolecular Organization of Membranes: Where Biology Meets Biophysics 210 $cFrontiers Media SA$d2018 215 $a1 electronic resource (150 p.) 225 1 $aFrontiers Research Topics 311 $a2-88945-409-6 330 $aBiological membranes protect cells and organelles from the surrounding environment, but serve also as organising platforms for physiological processes such as cell signalling. The hydrophobic core of membranes is composed of lipids and proteins influencing each other. Local membrane composition and properties define its molecular organisation and, in this way, regulate the function of all associated molecules. Therefore, studying interactions of components, biophysical properties and overall membrane dynamics provides essential information on its function in the context of cell activities. Such knowledge can contribute to biomedical fields such as pharmacology, immunology, neurobiology and many others. The goal of the Research Topic entitled ?Molecular organisation of membranes: where biology meets biophysics? was to provide a comprehensive platform for publishing articles, reviews and opinions focused on membrane organisation and the forces behind its heterogeneous and dynamic structure. We collected 11 works which cover topics as diverse as general membrane organisation models, membrane trafficking and signalling regulation, biogenesis of caveolae, protein-lipid interactions and the importance of membrane-associated tetraspanins networks. The prevalent theme was the existence of membrane nanodomains. To this point, new emerging technologies are presented which own the power to bring a novel insight on how membrane nanodomains are formed and maintained and what is their function. We believe that the collection of works in this Research Topic brings forward some important questions which will stimulate further research in this difficult but exciting field. 517 $aMolecular Organization of Membranes 610 $aCell Membrane 610 $aCaveolae 610 $aSuperresolution microscopy 610 $aNanodomains 610 $aMembrane trafficking 610 $aMembrane properties 610 $afluorescence microscopy 610 $aTetraspanins 700 $aMarek Cebecauer$4auth$01318741 702 $aDavid Holowka$4auth 906 $aBOOK 912 $a9910346747603321 996 $aMolecular Organization of Membranes: Where Biology Meets Biophysics$93033507 997 $aUNINA