LEADER 02476nam 2200397z- 450 001 9910346720503321 005 20210211 010 $a1000028834 035 $a(CKB)4920000000094496 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/45668 035 $a(oapen)doab45668 035 $a(EXLCZ)994920000000094496 100 $a20202102d2012 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aECG Based Analysis of the Ventricular Repolarisation in the Human Heart 210 $cKIT Scientific Publishing$d2012 215 $a1 online resource (XX, 224 p. p.) 225 1 $aKarlsruhe transactions on biomedical engineering / Ed.: Karlsruhe Institute of Technology / Institute of Biomedical Engineering 311 08$a3-86644-882-1 330 $aECG recordings provide diagnostic relevant information on the de- and repolarisation sequences of the heart. A modification of the repolarisation sequence is assumed to cause Torsades de Pointes. Especially drug induced effects on the repolarisation processes are in focus, since some non-cardiac drugs have been associated with sudden cardiac death in the 1990s. The analysis of the ventricular repolarisation using a set of parameters depicting the morphology of the T-wave is introduced in this work. Therefore, new methods of fully automatic patient-specific QRS detection, beat classification and precise T-wave delineation are presented. Using these methods, medical studies are investigated regarding the modification of the T-wave by different compounds. Also the impact of the heart rate on the morphology of the T-wave is part of this research.The reliable identification of ventricular ectopic beats allows an analysis of the influence of these beats on subsequent heart beats. It turned out that the morphology of subsequent heart beats can significantly be changed. This might give new information on the proarrythmical risk of ventricular ectopic beats. 606 $aTechnology: general issues$2bicssc 610 $aHRT 610 $aQT interval 610 $aQT prolongation 610 $aRepolarisation 610 $aT wave 615 7$aTechnology: general issues 700 $aBaas$b Tobias$4auth$01303447 906 $aBOOK 912 $a9910346720503321 996 $aECG Based Analysis of the Ventricular Repolarisation in the Human Heart$93027056 997 $aUNINA