LEADER 04096nam 2200889z- 450 001 9910346691103321 005 20231214132819.0 010 $a3-03897-913-9 035 $a(CKB)4920000000094758 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/46161 035 $a(EXLCZ)994920000000094758 100 $a20202102d2019 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aElectrospun and electrosprayed formulations for drug delivery /$fspecial issue editors, Ian S. Blagbrough, Gareth R. Williams 210 $cMDPI - Multidisciplinary Digital Publishing Institute$d2019 215 $a1 electronic resource (190 p.) 311 $a3-03897-912-0 330 $aThis book is comprised of important reviews and cutting-edge original research papers concerning electrospun and electrosprayed formulations in drug delivery. Electrospinning and electrospraying have, in recent years, attracted increasing attention in the pharmaceutical sector, with research in the area advancing rapidly. It is now possible to prepare extremely complex systems using multi-fluid processes, and to increase production rates to an industrial scale. Electrospun formulations can be produced under GMP conditions and are in clinical trials. In this volume, we explore a range of topics around electrospinning and electrospraying in controlled drug delivery. Four reviews cover the exciting potential of cyclodextrin-containing fibers and the many potential biomedical applications of electrospun fibers. The use of electrospinning to prepare amorphous systems and improve the dissolution rate and solubility of poorly soluble active ingredients is addressed, and the possibilities of such materials in tissue engineering are comprehensively covered. The six original research papers cover the effect of molecular properties on API release from Eudragit-based electrospun fibers; ferulic acid solid dispersions; electrospun medicines to treat psoriasis; scale up of electrospinning and its use to produce low-dose tablets; transepithelial permeation of drugs released from electrospun fibers, and the possibilities for the synergistic chemophotothermal treatment of cancer. 606 $aDrug delivery systems 606 $aElectrospinning 606 $aNanoparticles 610 $atissue engineering 610 $acyclodextrin 610 $apermeability 610 $apoly (vinylpyrrolidone-co-vinyl acetate) 610 $acrystalline 610 $aantibacterial 610 $adrug delivery 610 $ahomogenization 610 $acapsaicin 610 $acombination therapy 610 $ahigh-shear mixing 610 $acyclodextrin-inclusion complexes 610 $aamorphous 610 $ahigh-speed electrospinning 610 $aPMVE/MA 610 $aaqueous solubility enhancement 610 $asieve analysis 610 $aRaman mapping 610 $aEudragit 610 $ananofibers 610 $apsoriasis 610 $aPCL 610 $aessential oils 610 $aparameters 610 $aantibiotics 610 $axanthan gum 610 $acarvedilol 610 $aamorphous composite 610 $acoaxial electrospinning 610 $ainsoluble drug 610 $aNIR-triggered drug release 610 $afast dissolution 610 $aelectrospinning 610 $aoral drug delivery 610 $aelectrospun nanofibers 610 $apoly-cyclodextrin 610 $aTRPV1 610 $agallic acid 610 $asolid dispersion 610 $aphotothermal therapy 610 $adrug release 610 $aapplications 615 0$aDrug delivery systems. 615 0$aElectrospinning. 615 0$aNanoparticles. 676 $a615.1/9 702 $aBlagbrough$b I. S$g(Ian S.), 702 $aWilliams$b J. R. G.$f1978- 906 $aBOOK 912 $a9910346691103321 996 $aElectrospun and electrosprayed formulations for drug delivery$93401401 997 $aUNINA