LEADER 03029nam 22004933a 450 001 9910346691103321 005 20250203235428.0 010 $a9783038979135 010 $a3038979139 024 8 $a10.3390/books978-3-03897-913-5 035 $a(CKB)4920000000094758 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/46161 035 $a(ScCtBLL)bd93bd72-a122-4789-b4ab-da11da7c60da 035 $a(OCoLC)1126203902 035 $a(oapen)doab46161 035 $a(EXLCZ)994920000000094758 100 $a20250203i20192019 uu 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aElectrospun and Electrosprayed Formulations for Drug Delivery$fIan S. Blagbrough, Gareth R. Williams 210 $cMDPI - Multidisciplinary Digital Publishing Institute$d2019 210 1$aBasel, Switzerland :$cMDPI,$d2019. 215 $a1 electronic resource (190 p.) 311 08$a9783038979128 311 08$a3038979120 330 $aThis book is comprised of important reviews and cutting-edge original research papers concerning electrospun and electrosprayed formulations in drug delivery. Electrospinning and electrospraying have, in recent years, attracted increasing attention in the pharmaceutical sector, with research in the area advancing rapidly. It is now possible to prepare extremely complex systems using multi-fluid processes, and to increase production rates to an industrial scale. Electrospun formulations can be produced under GMP conditions and are in clinical trials. In this volume, we explore a range of topics around electrospinning and electrospraying in controlled drug delivery. Four reviews cover the exciting potential of cyclodextrin-containing fibers and the many potential biomedical applications of electrospun fibers. The use of electrospinning to prepare amorphous systems and improve the dissolution rate and solubility of poorly soluble active ingredients is addressed, and the possibilities of such materials in tissue engineering are comprehensively covered. The six original research papers cover the effect of molecular properties on API release from Eudragit-based electrospun fibers; ferulic acid solid dispersions; electrospun medicines to treat psoriasis; scale up of electrospinning and its use to produce low-dose tablets; transepithelial permeation of drugs released from electrospun fibers, and the possibilities for the synergistic chemophotothermal treatment of cancer. 606 $aDrug delivery systems 606 $aElectrospinning 606 $aNanoparticles 615 0$aDrug delivery systems. 615 0$aElectrospinning. 615 0$aNanoparticles. 676 $a615.1/9 700 $aBlagbrough$b Ian S$01786942 702 $aWilliams$b Gareth R 801 0$bScCtBLL 801 1$bScCtBLL 906 $aBOOK 912 $a9910346691103321 996 $aElectrospun and Electrosprayed Formulations for Drug Delivery$94319484 997 $aUNINA