LEADER 05131nam 2201453z- 450 001 9910346689003321 005 20231214133640.0 010 $a3-03921-266-4 035 $a(CKB)4920000000094779 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/61178 035 $a(EXLCZ)994920000000094779 100 $a20202102d2019 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aTranscriptional Regulation: Molecules, Involved Mechanisms and Misregulation 210 $cMDPI - Multidisciplinary Digital Publishing Institute$d2019 215 $a1 electronic resource (356 p.) 311 $a3-03921-265-6 330 $aTranscriptional regulation is a critical biological process involved in the response of a cell, a tissue or an organism to a variety of intra- and extra-cellular signals. Besides, it controls the establishment and maintenance of cell identity throughout developmental and differentiation programs. This highly complex and dynamic process is orchestrated by a huge number of molecules and protein networks and occurs through multiple temporal and functional steps. Of note, many human disorders are characterized by misregulation of global transcription since most of the signaling pathways ultimately target components of transcription machinery. This book includes a selection of papers that illustrate recent advances in our understanding of transcriptional regulation and focuses on many important topics, from cis-regulatory elements to transcription factors, chromatin regulators and non-coding RNAs, other than several transcriptome studies and computational analyses. 517 $aTranscriptional Regulation 610 $atranscription factor 610 $atranscription 610 $aself-incompatibility 610 $acytogenetics 610 $aepigenetics 610 $aselenocysteine 610 $atea 610 $aAP-2? 610 $anonsense-mediated decay 610 $atranscriptomics 610 $aAkt1 610 $apromoter 610 $acell metabolism 610 $apediveliger larvae 610 $aPatau Syndrome 610 $atristetraprolin (TTP) 610 $along non-coding RNA (lncRNA) 610 $apregnancy 610 $aG-quadruplex 610 $aglioblastoma 610 $aplacenta 610 $aPRDM gene family 610 $acircRNA-disease associations 610 $abioadhesive 610 $agene expression 610 $aCrassostrea gigas 610 $atranscription regulation 610 $acell differentiation 610 $aRNA interference 610 $atranscriptome 610 $ainflammatory response 610 $aFOXO1 610 $aAdiponectin 610 $aliquid chromatograph-tandem mass spectrometer (LC-MS/MS) 610 $aselenium 610 $aselenocysteine insertion sequence 610 $ainflammation 610 $aselenoproteins 610 $aresearch methods 610 $anutritional status 610 $astructures and functions 610 $aCRISPR/Cas9 610 $afertilization 610 $amelanin 610 $adifferentially expressed genes 610 $atyrosinase 610 $aposttranscriptional regulation 610 $amajor depressive disorder 610 $ahuman malignancies 610 $apathway 610 $aCDKN1C 610 $atranscription factors 610 $ap57Kip2 610 $aenhancer activity 610 $amouse 610 $adisorders 610 $ahigh-throughput RNA sequencing (RNA-Seq) 610 $aTCGA data analysis 610 $aRNA-seq 610 $aheterogeneous network 610 $ainsect 610 $aand drug design 610 $atherapeutic targets 610 $amechanisms 610 $aobesity 610 $aPacific oyster 610 $aRsh regulon 610 $acommon pathway 610 $aPax3 610 $asomatic mutations 610 $anutrition 610 $amolecular docking 610 $abioinformatics 610 $ainteractome 610 $along non-coding RNAs 610 $atranscriptional regulation 610 $aPteria penguin (Ro?ding 610 $aAdiponectin receptors 610 $atranscriptome profiling 610 $a1798) 610 $aN-acyl-l-homoserine lactone 610 $appGpp 610 $atumorigenesis 610 $asphingomonads 610 $ahuman 610 $adisease 610 $aadenosine and uridine-rich elements (AREs) 610 $aprogress and prospects 610 $amiR-25-3p 610 $aacute leukemia 610 $aNovosphingobium pentaromativorans US6-1 610 $amicroscopy 610 $acancer 610 $amolecular pathways 610 $acausal inference 700 $aCiccodicola$b Alfredo$4auth$01331914 702 $aCasamassimi$b Amelia$4auth 906 $aBOOK 912 $a9910346689003321 996 $aTranscriptional Regulation: Molecules, Involved Mechanisms and Misregulation$93040644 997 $aUNINA