LEADER 02555nam 2200517z- 450 001 9910346679103321 005 20231214133037.0 010 $a3-03897-538-9 035 $a(CKB)4920000000094876 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/42586 035 $a(EXLCZ)994920000000094876 100 $a20202102d2019 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aCalcium Signaling in Human Health and Diseases 210 $cMDPI - Multidisciplinary Digital Publishing Institute$d2019 215 $a1 electronic resource (462 p.) 311 $a3-03897-537-0 330 $aIntracellular Ca2+ signaling is witnessing an amazing resurgence of interest. In addition to traditional Ca2+ aficionados, an astonishing (and growing) number of colleagues from all around the world have started to devote a large part of their research to gain insights into the role of Ca2+ signaling in health and disease. This is why calcium ions interact with virtually every signal transduction pathway not only in mammalian cells, but also across the phylogenetic tree, thereby, driving or modulating most, if not all, cellular functions, ranging from fertilization to apoptosis, passing through learning and memory, cardiac contractility, and immune response. This book gathers a collection of original research articles and reviews by a number of renowned experts who aim to present the state of the art of many pathophysiological aspects of intracellular Ca2+ signaling, such as embryonic development, immune response, extracellular Ca2+ signaling, neoplastic transformation, muscle hypertrophy, pulmonary inflammation, and P2X receptor gating. 610 $aSTIM 610 $aintracellular Ca2+ oscillations 610 $aCa2+ signaling 610 $a5-trisphosphate receptors 610 $aneurovascular coupling 610 $acardiac contractility 610 $ainositol-1 610 $aSERCA 610 $aNMDA receptors 610 $acalcineurin 610 $aOrai 610 $aP2X receptors 610 $aCa2+-Sensing Receptor 610 $a4 610 $aimmune response 610 $acancer 610 $aCa2+-activated K+ channels 610 $amuscle hypertrophy 610 $aryanodine receptors 700 $aFrancesco Moccia (Ed.)$4auth$01287661 906 $aBOOK 912 $a9910346679103321 996 $aCalcium Signaling in Human Health and Diseases$93020269 997 $aUNINA