LEADER 02025nam 2200445z- 450 001 9910345964103321 005 20210211 035 $a(CKB)4920000000094073 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/55784 035 $a(oapen)doab55784 035 $a(EXLCZ)994920000000094073 100 $a20202102d2018 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aThe Pathogenetic Mechanisms at the Basis of Aortopathy Associated with Bicuspid Aortic Valve: Insights from "Omics", Models of Disease and Emergent Technologies 210 $cFrontiers Media SA$d2018 215 $a1 online resource (170 p.) 225 1 $aFrontiers Research Topics 311 08$a2-88945-395-2 330 $aThis forum of comprehensive reviews and research studies on distinct aspects of the pathophysiology of BAV aortopathy provides both the state of the art in the knowledge on this complex disease and novel insights into its causes and consequences. The present collection of focused papers also envisions and proposes new therapeutic strategies, novel biomarkers and original risk stratification criteria, for the improvement of patient management. 517 $aPathogenetic Mechanisms at the Basis of Aortopathy Associated with Bicuspid Aortic Valve 606 $aPhysiology$2bicssc 610 $a4DFlow analysis 610 $aaortic root 610 $aaortic surgery 610 $aaortopathy 610 $abicuspid aortic valve 610 $aendothelial cells 610 $amicroRNAs 610 $asmooth muscle cells 615 7$aPhysiology 700 $aAlessandro Della Corte$4auth$01329488 702 $aAmalia Forte$4auth 906 $aBOOK 912 $a9910345964103321 996 $aThe Pathogenetic Mechanisms at the Basis of Aortopathy Associated with Bicuspid Aortic Valve: Insights from "Omics", Models of Disease and Emergent Technologies$93039505 997 $aUNINA